30413-61-7Relevant articles and documents
INHIBITORS FOR THE Β-CATENIN / T-CELL FACTOR PROTEIN–PROTEIN INTERACTION
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Page/Page column 37; 38, (2019/10/23)
Disclosed are inhibitors for the β-catenin/T-cell factor interaction. The inhibitors are selective for β-catenin/T-cell factor over β-catenin/cadherin and β-catenin/APC interactions. Methods of using the disclosed compounds to treat cancer are also disclosed.
Efficient synthesis of 2-pyridylenynes and application in cobalt-catalysed benzannulation reactions
R?se, Philipp,Pünner, Florian,Hilt, Gerhard,Harms, Klaus
, p. 1101 - 1104 (2013/06/27)
The cobalt-catalysed benzannulation of 2-pyridine-substituted enynes gave 2,3-bis(2-pyridyl)styrenes in moderate yields. The reaction with dibromomethane as well as diiodomethane generated the corresponding planar-chiral bispyridinium salts in good yields
Synthesis of functionalized arylpyridines and -pyrimidines by domino [4+2]/retro [4+2] cycloadditions of electron-rich dienes with alkynylpyridines and -pyrimidines
Abid, Obaid-Ur-Rahman,Nawaz, Muhammad,Ibad, Muhammad Farooq,Khera, Rasheed Ahmad,Iaroshenko, Viktor,Langer, Peter
scheme or table, p. 2185 - 2191 (2011/04/26)
Aryl-substituted pyridines and pyrimidines were prepared by [4+2] cycloadditions of alkynyl-substituted pyridines and -pyrimidines with electron-rich dienes. The reactions proceed by formation of a bridged cycloadduct and subsequent thermal extrusion of ethylene. The pyridine moiety plays a crucial role for the success of the reaction.
