30426-16-5

Upstream product

• 5351-69-9 4-Phenyl-3-thiosemicarbazide 
• 1499-21-4 Diphenylphosphinic chloride 
• 103-72-0 phenyl isothiocyanate 
• 6779-66-4 diphenylphosphinic acid hydrazide 

Downstream Products

• 40970-60-3 diphenylphosphinic acid [4-(4-bromo-phenyl)-3-phenyl-3H-thiazol-2-ylidene]-hydrazide 
• 40970-58-9 diphenylphosphinic acid (3,4-diphenyl-3H-thiazol-2-ylidene)-hydrazide 
• 40970-67-0 diphenylphosphinic acid 4-phenyl-2-phenylimino-thiazol-3-ylamide 

Relevant academic research and scientific papers

Phosphorhydrazide inhibitors: Toxicological profile and antimicrobial evaluation assay, molecular modeling and QSAR study

A series of phosphorhydrazide (PHA) derivatives with the (X = O,S) P-NHα-NHβ-C (X = O,S) skeleton (1-23) were synthesized and characterized by spectral techniques. A single crystal X-ray study of 4 and 21 provided confirmation of the

Correlation of the catalytic activity of pyridines and N-pyridine oxides with their basicity

N-Pyridine oxides much stronger catalyze formation of organophosphorus thiosemicarbazides than pyridines, even though these two groups of catalysts compare in basicity. Separate correlations were found for pyridines and N-pyridine oxides of the catalytic

V. Electronic Structure of Polyfluoroaromatic Silanes and Related Hydrocarbons

Effect of substituents on the phosphorus atom in diarylphosphinic hydrazides on their reactivity toward phenyl isothiocyanate in nitrobenzene in the presence of pyridine at 298-328 K is described by the Hammett equation including ?P constants.

Effect of the medium on noncatalytic semicarbazide formation

The dependence of the logarithms of the rate constants of the reaction of diphenylphosphinic hydrazide with phenyl isothiocyanate on the nature of the solvent is well described by the four-parameter Koppel'-Pal'm equation, which allows quantitative analys

Qualitative Assessment of the Catalytic Effect of Tertiary Phosphines

The catalytic effect of trialkylphosphine oxides on reaction of diphenylphosphininc hydrazide with phenyl isocyanate in benzene at 25 deg C was evaluated. The catalytic effect was found to be linearly related to the electron-donor factor E, the sum of the Taft constants ?* and the constants ?P of the substituents in the phosphorus atom.

Effect of substrate structure on N-methylimidazole-catalyzed formation of thiosemicarbazides

The kinetics of the N-methylimidazole-catalyzed reactions of aryl isothiocyanates with diphenylphosphinic hydrazide in benzene at 25°C were studied. N-Methylimidazole exhibits a high catalytic activity depending on the structure of the isothiocyanates. Th

Catalytic Activity of Sterically Hindered Heterocyclic Tertiary Amines in Thiosemicarbazide Formation

Kinetics of the reaction of diphenylphosphinic hydrazide with phenyl isothiocyanate in benzene at 25°C in the presence of 2-alkyl-substituted pyridines and N-methylbenzimidazoles were studied. Steric and inductive components of the nucleophilicity of thes

Dialkyltin Diacylates as Bifunctional Catalysts in Reaction of Diphenylphosphinic Hydrazide with Phenyl Isothiocyanate

Dialkyltin diacylates are the most effective catalysts of thiosemicarbazide formation, among the organotin compounds studied. Alkyltin acylates far exceed in activity a mixture of alkyl(phenyl)tin derivatives with carboxylic acid esters of the same concen

Kinetics of Reaction of Diphenylphosphinic Dihydrazide with Electrophilic Reagents in the Presence of Organic Bases

Kinetics of the reactions of diphenylphosphinic dihydrazide with mesityl isothiocyanate, phenyl isothiocyanate, and picryl chloride in the presence of nitrogen-, oxyden-, and sulfur-containing organic bases in benzene at 25°C are studied. Accelerating effect of nitrogen- and oxygen-containing bases in the reactions of diphenylphosphinic hydrazide with all the studied electrophilic reagents correlates with the ability of these catalysts to form hydrogen bonds (pKHB). Sulfur-containing compounds practically do not exhibit catalytic properties in the studied systems. With increasing substrate reactivity, the catalytic effect of organic catalysts decreases.

Catalytic Effects of Heterocyclic Bases in Thiosemicarbazide Formation

The kinetics of the reaction of diphenylphosphinic hydrazide with phenyl isothiocyanate catalyzed by pyridines, N-substituted azoles, and N-pyridine oxides in benzene at 25°C was studied. The catalytic activity of the heterocyclic bases increases in the o