30432-63-4Relevant academic research and scientific papers
Selectivity in the N- and/or C-Alkylation of Schiff Bases Catalyzed by Crown Ether
Akabori, Sadatoshi,Ohtomi, Michiko,Shimada, Kazuhide,Takemura, Ayami
, p. 1273 - 1274 (1981)
The reaction of anions derived from Schiff bases (N-(α-methylbenzylidene)aniline and N-cyclohexylideneaniline) with ethyl iodide or diethyl sulfate in aprotic solvents, in the presence of 18-crown-6, is found to give a high ratio of N/(N+C) or C/(N+C) alkylation when conducted in benzene or in dioxane.
Iodine-mediated 1,2-aryl migration of primary benzhydryl amines
Chang, Junbiao,Du, Yangxu,Hao, Wei,Hou, Jiao,Lu, Qing,Yu, Wenquan
supporting information, p. 16223 - 16226 (2021/09/22)
An iodine-mediated 1,2-aryl migration reaction of primary benzhydryl amines under transition metal-free conditions has been achieved. The crude imines generated by this rearrangement reaction can be directly transformed into various aromatic secondary ami
Substrate-dependent regiodivergent three-component condensation of 1H-pyrrole-2,3-diones, malononitrile and 4-hydroxyquinolin-2(1H)-ones
Salnikova, Tatyana V.,Sabitov, Andrey A.,Dmitriev, Maksim V.,Maslivets, Andrey N.,Rubin, Michael
, (2021/05/05)
An efficient regiodivergent three-component condensation of 1H-pyrrole-2,3-diones, malononitrile, and 4-hydroxyquinolin-2(1H)-ones was developed. The reaction can lead to the formation of spiro[pyrano[3,2-c]quinoline-4,3′-pyrrole] derivatives or the substituted 1,5-dihydropyrrole-2-ones depending on the substituents of 1H-pyrrole-2,3-diones and reaction conditions.
Iron-catalysed 1,2-aryl migration of tertiary azides
Wei, Kaijie,Yang, Tonghao,Chen, Qing,Liang, Siyu,Yu, Wei
, p. 11685 - 11688 (2020/10/19)
1,2-Aryl migration of α,α-diaryl tertiary azides was achieved by using the catalytic system of FeCl2/N-heterocyclic carbene (NHC) SIPr·HCl. The reaction generated aniline products in good yields after one-pot reduction of the migration-resultant imines.
An efficient proline-based homogeneous organocatalyst with recyclability
Li, Qiang,Li, Yuan,Wang, Jingdong,Lin, Yingjie,Wei, Zhonglin,Duan, Haifeng,Yang, Qingbiao,Bai, Fuquan,Li, Yaoxian
supporting information, p. 827 - 831 (2018/02/03)
In this work, a homogeneous organocatalyst was developed for the asymmetric reduction of imines. This catalyst could be separated by cyclodextrin-modified Fe3O4@SiO2 magnetic nanoparticles and then released back into a fre
From Ketones, Amines, and Carbon Monoxide to 4-Quinolones: Palladium-Catalyzed Oxidative Carbonylation
Wu, Jiwei,Zhou, Yuchen,Wu, Ting,Zhou, Yi,Chiang, Chien-Wei,Lei, Aiwen
supporting information, p. 6432 - 6435 (2017/12/08)
A novel method of palladium-catalyzed oxidative carbonylation of ketones, amines, and carbon monoxide for the synthesis of 4-quinolones has been developed. This protocol provides a straightforward route to construct useful 4-quinolone derivatives from ine
Synthesis of 3-acetyl-4-hydroxy-1-phenylpyridin-2(1H)-one derivatives
Nikam,Kappe
, p. 215 - 220 (2015/01/30)
The cyclization of aryl ketone anilides 3 with diethyl malonate to affords 4-hydroxy-6-phenyl-6H-pyrano [3,2-c]-pyridin-2,5-diones 4 in good yields. 3-Acetyl-4-hydroxy-1-phenylpyridin-2(1H)-ones 5 are obtained by ring-opening reaction of 4-hydroxy-6-pheny
Triazole-Au(I) complexes: A new class of catalysts with improved thermal stability and reactivity for intermolecular alkyne hydroamination
Duan, Haifeng,Sengupta, Sujata,Petersen, Jeffrey L.,Akhmedov, Novruz G.,Shi, Xiaodong
supporting information; experimental part, p. 12100 - 12102 (2009/12/30)
(Chemical Equation Presented) A series of 1,2,3-triazole-bound cationic Au(I) catalysts have been synthesized, and their structures have been characterized by X-ray crystallography. Variable-temperature NMR studies revealed dynamic triazole-Au cation coor
Development of highly enantioselective new Lewis basic N-formamide organocatalysts for hydrosilylation of imines with an unprecedented substrate profile
Wu, Pengcheng,Wang, Zhouyu,Cheng, Mounuo,Zhou, Li,Sun, Jian
experimental part, p. 11304 - 11312 (2009/04/06)
l-Pipecolinic acid derived N-formamides have been developed as new Lewis basic organocatalysts that promote the asymmetric reduction of N-aryl ketimines using trichlorosilane as the reducing agent. The substituent on N4 of the piperazinyl backbone and the
Rationally-designed S-chiral bissulfinamides as highly enantioselective organocatalysts for reduction of ketimines
Pei, Dong,Zhang, Yu,Wei, Siyu,Wang, Meng,Sun, Jian
supporting information; experimental part, p. 619 - 623 (2009/04/21)
We recently reported the first example of S-chiral organocatalysts, that are highly efficient and enantioselective in substoichometric amounts, and which use a chiral monosulfinamide group as Lewis base to activate trichlorosilane (HSiCl3) to reduce N-arylketimines. Aplausible mechanism involving two molecules of the monosulfinamde catalyst for the activation of HSiCl 3 prompted us to design S-chiral bissulfinamides as new catalysts. We herein describe our findings that an easily prepared S-chiral bissulfinamide bearing a five-methylene linkage not only inherited the excellent substrate generality from the monosulfinamide catalysts, but also exhibited further improved enantioselectivity.
