30433-74-0Relevant academic research and scientific papers
Diels-Alder Reactions of 1,2,4-Triazines. Synthesis of Thienopyridines and 3,4-Dihydro-2H-thiopyranopyridines from 6-(Alkynylthio)-1,2,4-triazines
Taylor, Edward C.,Macor, John E.
, p. 4984 - 4989 (2007/10/02)
Intramolecular Diels-Alder reactions of 6-(alkynylthio)-1,2,4-triazines are shown to give 2,3-dihydrothienopyridines and 3,4-dihydro-2H-thiopyranopyridines. 1-Oxo-2,3-dihydrothienopyridines synthesized in this fashion from the corresp
Thienopyridine derivatives useful in treating gastric ulcers
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, (2008/06/13)
A compound of the formula: STR1 (wherein R1 is hydrogen, C1 -C5 alkyl, C1 -C5 alkoxy, C1 -C5 alkoxycarbonyl, or trifluoromethyl; R2 is hydrogen, C1 -C5 alkoxycarbonyl, C6 -C12 aryloxycarbonyl, C1 -C5 alkanoyloxy-C1 -C5 alkyl, C1 -C5 alkoxycarbonyloxy-C1 -C5 alkyl, C1 -C5 acylamino-C1 -C5 alkyl, 2-hydroxy-1-C2 -C5 alkenyl, phthalimido-C1 -C5 alkyl, halogeno-C1 -C5 alkoxycarbonyl-C1 -C5 alkyl, hydroxy-C1 -C5 alkyl, C1 -C5 alkylthio-C1 -C5 alkyl, or C1 -C5 alkylsulfinyl-C1 -C5 alkyl; STR2 m is an integer of 0 or 1; R3 and R4 each is hydrogen, halogen, cyano, C1 -C5 alkyl, amino, C1 -C5 alkoxy, C6 -C12 aryl-C1 -C5 alkoxy, C1 -C5 alkoxycarbonyl, fluoro-C1 -C5 alkoxy, C1 -C5 alkanoylamino, or carbamoyl) or its salt, being useful as antiulcer agents, is provided.
NOVEL INTRAMOLECULAR DIELS-ALDER REACTIONS WITH ALKYNYLTHIO DERIVATIVES OF 1,2,4-TRIAZINES. NEW ROUTES TO THIENOPYRIDINES AND THIENOPYRIDINES
Taylor, Edward C.,Macor, John E.
, p. 2419 - 2422 (2007/10/02)
S-Alkylation of 1,2,4-triazine-6-thiones with 4-iodobutyne, followed by oxidation to the sulfoxide and intramolecular cycloaddition (at room temperature), gives 2,3-dihydrothienopyridines, which are readily dehydrated with acetic anhydride to thien
The Thienopyridine Reissert Compound
Bass, R. J.,Popp, F. D.,Kant, J.
, p. 1119 - 1120 (2007/10/02)
Thienopyridine has been converted to 6-benzoyl- and 6-carbethoxy-7-cyano-6,7-dihydrothienopyridine.Alkylation, condensation, Michael addition, and cyclo addition reactions of these Reissert type compounds have been carried out.
