304436-21-3

Upstream product

• 244056-97-1 Benzyl 2-allyl-3-oxo-1-piperidinecarboxylate 

Downstream Products

• 304436-20-2 benzyl (3aS,7aS)-2-hydroxy-2-[(4-oxo-3(4H)-quinazolinyl)methyl]hexahydrofuro[3,2-b]pyridine-4(2H)-carboxylate 
• 304436-19-9 benzyl (3aS,7aS)-2-(bromomethyl)-2-methoxyhexahydrofuro[3,2-b]pyridine-4(2H)-carboxylate 
• 304436-18-8 benzyl (3aS,7aS)-2-(bromomethyl)hexahydrofuro[3,2-b]pyridine-4(2H)-carboxylate 
• 304436-17-7 benzyl (2S,3S)-2-allyl-3-hydroxypiperidine-1-carboxylate 
• 32434-44-9 (+)-isofebrifugine 
• 184535-16-8 (S)-1-benzyloxycarbonyl-2-(2-propenyl)piperidine 
• 244056-94-8 benzyl (2R,3R)-2-allyl-3-hydroxypiperidine-1-carboxylate 
• 244056-97-1 Benzyl 2-allyl-3-oxo-1-piperidinecarboxylate 

Relevant academic research and scientific papers

Asymmetric synthesis of febrifugine and isofebrifugine using yeast reduction

The antimalarial agents febrifugine ((+)-1) and isofebrifugine ((+)-2) were asymmetrically synthesized from chiral piperidin-3-ol ((+)-4), which was prepared by the reductive dynamic optical resolution of the 3-piperidone derivatives ((±)-3) using baker's