304449-84-1

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 108-46-3 recorcinol 
• 552-30-7 trimellitic Anhydride 
• 76823-03-5 5-carboxyfluoroscein 
• 500533-95-9 5-carboxyfluorescein 

Relevant academic research and scientific papers

In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives

We describe the synthesis and characterization of two acetazolamide derivatives containing either a charged fluorophore or an albumin-binding moiety, which restrict binding to carbonic anhydrase IX and XII present on tumor cells. In vivo studies showed th

Design, synthesis, and characterization of fluorescent cobalamin analogues with high quantum efficiencies

Cobalamin tethered to fluorescein or Rhodamine 6G has been synthesized and characterized. The fluorophore is conjugated to the ribose-5-OH of cobalamin through a rigid linker to prevent the fluorophore from folding back through space and interacting with

Synthesis and evaluation of tripodal peptide analogues for cellular delivery of phosphopeptides

Tripodal peptide analogues were designed on the basis of the phosphotyrosine binding pocket of the Src SH2 domain and assayed for their ability to bind to fluorescein-labeled phosphopeptides. Fluorescence polarization assays showed that a number of amphip

PYRIMIDO[4,5-B]INDOL DERIVATIVES AS PDHK1 INHIBITORS

The present invention relates to piperidine derivatives of formula (I) wherein R1, and R2 are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to p

Lipophilic electrophoretic probes

Compounds, compositions, and methods for labeling membranes are disclosed. Compounds of formula G-L-E are described wherein G is a lipophilic group, L is a cleavable linkage and E is an electrophoretic group. The compounds become associated with membranes