304481-60-5 Usage
Uses
Used in Pharmaceutical Industry:
KM 91104 is used as a V-ATPase inhibitor for targeting the a3-b2 subunit protein-protein interaction of V-ATPase. This inhibition can potentially be utilized in the development of treatments for various diseases and conditions where V-ATPase plays a significant role.
Used in Cancer Research:
KM 91104 is used as a research tool for studying the role of V-ATPase in cancer cell metabolism and proliferation. By inhibiting the a3-b2 subunit protein-protein interaction of V-ATPase, it can help researchers understand the underlying mechanisms of cancer development and progression, potentially leading to the discovery of novel therapeutic strategies.
Used in Drug Development:
KM 91104 is used as a lead compound in the development of new drugs targeting V-ATPase. Its specificity for the a3-b2 subunit protein-protein interaction makes it a valuable starting point for designing more potent and selective inhibitors with improved pharmacological properties.
Used in Cell Biology Research:
KM 91104 is used as a cell biology research tool for studying the role of V-ATPase in various cellular processes, such as endocytosis, exocytosis, and vesicular trafficking. By inhibiting the a3-b2 subunit protein-protein interaction, it can help researchers gain insights into the molecular mechanisms underlying these processes and their regulation.
Check Digit Verification of cas no
The CAS Registry Mumber 304481-60-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,4,4,8 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 304481-60:
(8*3)+(7*0)+(6*4)+(5*4)+(4*8)+(3*1)+(2*6)+(1*0)=115
115 % 10 = 5
So 304481-60-5 is a valid CAS Registry Number.
304481-60-5Relevant academic research and scientific papers
Mechanistic differences between in vitro assays for hydrazone-based small molecule inhibitors of anthrax lethal factor
Hanna, M. Leslie,Tarasow, Theodore M.,Perkins, Julie
, p. 50 - 58 (2008/09/18)
A systematically generated series of hydrazones were analyzed as potential inhibitors of anthrax lethal factor. The hydrazones were screened using one UV-based and two fluorescence-based in vitro assays. The study identified several inhibitors with IC50 values in the micromolar range, and importantly, significant differences in the types of inhibition were observed with the different assays.
