304481-86-5

Basic information

• Product Name: (E)-4-[2-(4-nitrobenzoyl)hydrazino]-4-oxo-2-butenoic acid
• Synonyms: (E)-4-[2-(4-nitrobenzoyl)hydrazino]-4-oxo-2-butenoic acid;(2E)-4-{2-[(4-nitrophenyl)carbonyl]hydrazinyl}-4-oxobut-2-enoic acid
• CAS NO: 304481-86-5
• Molecular Formula: C11H8N3O6-
• Molecular Weight: 278.19772
• Mol File: 304481-86-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 657°Cat760mmHg
• Flash Point: 351.1°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 3.73E-18mmHg at 25°C
• CAS DataBase Reference: (E)-4-[2-(4-nitrobenzoyl)hydrazino]-4-oxo-2-butenoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-[2-(4-nitrobenzoyl)hydrazino]-4-oxo-2-butenoic acid(304481-86-5)
• EPA Substance Registry System: (E)-4-[2-(4-nitrobenzoyl)hydrazino]-4-oxo-2-butenoic acid(304481-86-5)

Safety Data

• Hazardous Substances Data: 304481-86-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H9N3O6/c15-9(5-6-10(16)17)12-13-11(18)7-1-3-8(4-2-7)14(19)20/h1-6H,(H,12,15)(H,13,18)(H,16,17)/p-1

Upstream product

• 108-31-6 maleic anhydride 
• 636-97-5 N-amino-(4-nitrophenyl)carboxamide 

Relevant articles and documents

The Synthesis of (1,3,4-Oxadiazol-2-yl)Acrylic Acid Derivatives with Antibacterial and Protistocidal Activities

A series of new 1,3,4-oxadiazol-2-yl-acrylic acids was synthesized by cyclization of 4-(2-R-hydrazino)- 4-oxo-2-butenic acids, and their antibacterial and protistocidal activities were studied. The p-substituted benzyl derivatives in the Z-form were shown to exhibit a high protistocidal activity, which exceeded that of the reference drug Baycox (toltrazuril) by several times, whereas the 3-hydroxy-2-naphthyl derivative, in addition to a very high protistocidal activity, also exhibited a moderate antibacterial activity.

Substituted amides and hydrazides of 1,4-dicarboxylic acids. Part 7. Synthesis and pharmacological activity of some maleic, succinic, and phthalic acid acylhydrazides

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