3045-99-6

Upstream product

• 124462-31-3 4,4a,5,6,7,8,9,9a-octahydro-3-phenyl-9a-(trimethylsiloxy)cyclohept-1,2-oxazine 
• 139373-25-4 Trifluoro-methanesulfonate(1-methoxycarbonyl-2-oxo-cycloheptylmethyl)-phenyl-trimethylsilanylmethyl-sulfonium; 

Downstream Products

• 3008-39-7 cycloheptane-1,2-dione 
• 21726-02-3 1,2-Dihydroxy-2-(β-amino-β-phenyl-aethyl)-cycloheptan 
• 21725-87-1 3-phenyl-1-oxa-2-aza-spiro[4.6]undec-2-en-6-one 

Relevant academic research and scientific papers

A New Fragmentation Reaction of γ-Oxosulfonium Methylides

Reactions of sulfonium methylides attached to a 5- or 6-membered cycloalkanone undergo the ring-fission as a major reaction course to give α-methylene-ω-(phenylthio)carboxylates, whereas sulfonium methylides attached to a larger ring give α-methylenecycloalkanones predominantly.Reactions of the acyclic compounds are also examined.

Transition Metal- and Acid-Induced Transformations of 6-Siloxy-Substituted 5,6-Dihydro-4H-1,2-oxazines: Preparation of Pyrroles, Nitrones, 1,4-Dicarbonyl Compounds and Derivatives Thereof

A variety of 6-siloxy-substituted 5,6-dihydro-4H-1,2-oxazines (abbreviation: 1,2-oxazines) 1, 3 could be transformed into di- and trisubstituted pyrroles 2, 4 by means of molybdenum hexacarbonyl.The mechanism of this deoxygenating ring contraction is discussed.With two bicyclic 1,2-oxazines an acid-catalyzed fragmentation affording α-methylenecycloalkanones 7 has been observed, while other 1,2-oxazines rearrange in methanolic acid to give nitrones 9, 10.The desilylation of 6-siloxy-substituted 1,2-oxazines 1.3 employing NEt3*3HF is a very general and smooth process providing 6-hydroxy-1,2-oxazines 11, 12 or their corresponding acyclic tautomers 13, 14 in high yields.For two examples of 11 deoximations by use of formalin could be achieved with moderate efficiency giving 1,4-dicarbonyl compounds 15.