3008-39-7

Basic information

• Product Name: cycloheptane-1,2-dione
• Synonyms: cycloheptane-1,2-dione;Einecs 221-121-7
• CAS NO: 3008-39-7
• Molecular Formula: C₇H₁₀O₂
• Molecular Weight: 126.1531
• EINECS: 221-121-7
• Mol File: 3008-39-7.mol
• Article Data: 12

Chemical Properties

• Melting Point: -40°C
• Boiling Point: 194.28°C (rough estimate)
• Flash Point: 77°C
• Appearance: /
• Density: 1.0583
• Vapor Pressure: 0.157mmHg at 25°C
• Refractive Index: 1.4689 (estimate)
• CAS DataBase Reference: cycloheptane-1,2-dione(CAS DataBase Reference)
• NIST Chemistry Reference: cycloheptane-1,2-dione(3008-39-7)
• EPA Substance Registry System: cycloheptane-1,2-dione(3008-39-7)

Safety Data

• Hazardous Substances Data: 3008-39-7(Hazardous Substances Data)

Usage

Uses

1,2-Cycloheptanedione is a reagent in the synthesis of 3,3’-Polymethylene-2,2’-bibenzo[b]-1,10-phenanthrolines.

InChI:InChI=1/C7H10O2/c8-6-4-2-1-3-5-7(6)9/h1-5H2

Upstream product

• 502-42-1 cycloheptanone 
• 109459-47-4 C₉H₁₄O₃ 
• 109459-51-0 1,4-Dioxa-spiro[4.6]undecan-6-ol 
• 1728-24-1 1,4-dioxaspiro[4,6]undec-6-ene 
• 77256-26-9 2-Iodocycloheptanone 
• 186581-53-3 diazomethane 
• 530-97-2 1,2-cycloheptane dione dioxime 
• 56-23-5 tetrachloromethane 
• 2050-20-6 diethyl pimelate 
• 143-19-1 sodium Oleate 
• 98954-17-7 2,7-dimethylene-cycloheptanone 
• 3045-99-6 2-methylenecycloheptanone 
• 89874-32-8 1,4-dioxaspiro<4,6>undecan-6-one 
• 52190-36-0 2-(methylthio)cycloheptanone 

Downstream Products

• 125420-07-7 4-Benzoyl-6,7,8,9-tetrahydro-1,3-diphenyl-5H-benzocyclohepten-5-on 
• 96304-36-8 2-((S)-2-Methoxymethyl-pyrrolidin-1-yl)-cyclohept-2-enone 
• 88396-10-5 3-(p-Tolyl)-6,7,8,9-tetrahydro-5H-cyclohepta-1,2,4-triazin 
• 125420-13-5 6,7,8,9-Tetrahydro-4-(4-methyl-benzoyl)-1-(4-methyl-phenyl)-3-phenyl-5H-benzocyclohepten-5-on 
• 125420-09-9 4-Benzoyl-6,7,8,9-tetrahydro-3-(4-methoxy-phenyl)-1-phenyl-5H-benzocyclohepten-5-on 
• 125420-14-6 4-(4-Chlor-benzoyl)-1-(4-chlor-phenyl)-6,7,8,9-tetrahydro-3-phenyl-5H-benzocyclohepten-5-on 
• 125420-12-4 4-Benzoyl-6,7,8,9-tetrahydro-3-(4-nitro-phenyl)-1-phenyl-5H-benzocyclohepten-5-on 
• 125420-08-8 4-Benzoyl-6,7,8,9-tetrahydro-3-(4-methyl-phenyl)-1-phenyl-5H-benzocyclohepten-5-on 
• 125420-11-3 4-Benzoyl-3-(4-brom-phenyl)-6,7,8,9-tetrahydro-1-phenyl-5H-benzocyclohepten-5-on 
• 125420-10-2 4-Benzoyl-3-(4-chlor-phenyl)-6,7,8,9-tetrahydro-1-phenyl-5H-benzocyclohepten-5-on 
• 125420-15-7 4-(4-Brom-benzoyl)-1-(4-brom-phenyl)-6,7,8,9-tetrahydro-3-phenyl-5H-benzocyclohepten-5-on 
• 530-97-2 1,2-cycloheptane dione dioxime 
• 80276-70-6 1,2-cycloheptane dione monoxime 
• 42063-01-4 2-benzylidene-cycloheptanone 

Relevant articles and documents

A VERY EFFICIENT PREPARATION OF 1,2-DIKETONES

Treatment of α-thiomethylketones with CuCl2-CuO in aqueous acetone affords the corresponding 1,2-dicarbonyl compounds.

SELECTIVE ANDROGEN RECEPTOR MODULATORS

This invention provides compounds of Formula (I), (Ia), (Ib), (Ic), (II), (IIa) or (III) and or salts thereof, pharmaceutical compositions comprising a compound of Formula (I), (Ia), (Ib), (Ic), (II), (IIa) or (III) and a pharmaceutically acceptable excipient, methods of modulating the androgen receptor, methods of treating diseases beneficially treated by an androgen receptor modulator (e.g., sarcopenia, prostate cancer, contraception, type II diabetes related disorders or diseases, anemia, depression, and renal disease) and processes for making compounds of Formula (I), (Ia), (Ib), (Ic), (II), (IIa) or (III) and intermediates useful in the preparation of same.

A novel synthesis of α-hydroxy- and α,α′- dihydroxyketone from α-iodo and α,α′-diiodo ketone using photoirradiation

A novel reaction of α-iodo ketone (α-iodocycloalkanone, α-iodo-β-alkoxy ester, and α-iodoacyclicketone) with irradiation under a high-pressure mercury lamp gave the corresponding α-hydroxyketone in good yields. In the case of α,α′- diiodo ketone, α,α′-dihydroxyketone which little has been reported until now was obtained. This reaction affords a new, clean and convenient synthetic method for α-hydroxy- and α,α′- dihydroxyketone.

Mechanochemical Oxidation of Organic Model Compounds by Means of Potassium Permanganate

Systematical investigation of solvent-free oxidations of organic model compounds with potassium permanganate on inorganic carriers leads to conclusion, that mechanochemical stimulation can induce oxidations. In case of the benzyl-type arenes these conversions are selective at good yields. Olefines react to carbonic acids. The presence of water enhances the yield of almost all educts.