30453-21-5

Basic information

• Product Name: Bis(3-hydroxypropyl) persulfide
• Synonyms: 3,3'-Dithiobis(1-propanol);Bis(3-hydroxypropyl) persulfide
• CAS NO: 30453-21-5
• Molecular Formula: C₆H₁₄O₂S₂
• Molecular Weight: 182.3
• Mol File: 30453-21-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 160 °C(Press: 0.8 Torr)
• Appearance: /
• Density: 1.211±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.56±0.10(Predicted)
• CAS DataBase Reference: Bis(3-hydroxypropyl) persulfide(CAS DataBase Reference)
• NIST Chemistry Reference: Bis(3-hydroxypropyl) persulfide(30453-21-5)
• EPA Substance Registry System: Bis(3-hydroxypropyl) persulfide(30453-21-5)

Safety Data

• Hazardous Substances Data: 30453-21-5(Hazardous Substances Data)

Usage

General Description

Bis(3-hydroxypropyl) persulfide is a chemical compound containing two hydroxypropyl groups bonded to a persulfide (S2O2) group. It is commonly used as a crosslinking agent in the production of rubber and related materials. It acts as a sulfur donor in the vulcanization process, helping to form strong, durable bonds between polymer chains. Bis(3-hydroxypropyl) persulfide also has potential applications in the medical field, as it has been studied for its potential as an anti-cancer agent due to its ability to induce apoptosis in cancer cells. Overall, this compound plays a crucial role in the production of rubber products and demonstrates potential for medical applications.

Upstream product

• 19721-22-3 3-sulfanylpropanol 
• 67066-33-5 3-hydroxypropyl thiocyanate 
• 2986-30-3 S-(3-hydroxy-propyl)-isothiourea 
• 24308-28-9 1,3-propanesultine 
• 5684-29-7 1,2-oxathiolane 
• 627-30-5 1-chloro-3-hydroxypropane 

Downstream Products

• 19721-22-3 3-sulfanylpropanol 
• 24308-28-9 1,3-propanesultine 
• 15909-83-8 3-hydroxypropanesulfonic acid 
• 598-02-7 Diethyl phosphate 
• 762-04-9 phosphonic acid diethyl ester 

Relevant articles and documents

Preparation and application of polymerizable disulfide capable of reducing volume shrinkage

The invention relates to preparation and application of polymerizable disulfide capable of reducing volume shrinkage. The synthesis comprises the following steps: adding aliphatic sulfhydrate with reactive hydrogen and sodium iodide into a reactor, adding hydrogen peroxide dropwise under the condition of magnetic stirring and reacting to obtain a product A; and putting the product A and organic alkali into a reaction bottle and adding an acyl chloride compound dropwise under the action of magnetic stirring to obtain the polymerizable disulfide. The preparation and the application of the polymerizable disulfide capable of reducing volume shrinkage have the following beneficial effects: (1) the polymerizable disulfide can obviously reduce the volume shrinkage in the photopolymerization process and provides a new method for reducing volume shrinkage; and (2) the polymerizable disulfide can take part in photopolymerization and also can initiate photopolymerization.

Polydopamine as a Catalyst for Thiol Coupling

In biological systems, disulfide bonds are formed efficiently under mild conditions without the release of harmful byproducts. Inspired by nature, we report a biomimetic polydopamine (PDA) catalyst for oxidative thiol coupling. This reaction was accelerated with only a small amount of PDA particles in neutral, weakly alkaline, and even weakly acidic aqueous media at room temperature under an air atmosphere. The catalytic particles were facilely separated and were reused without a decrease in activity. The entire process is totally biofriendly, including the synthesis of the PDA particles. This route is especially useful for the synthesis of pharmaceutical molecules. S-imulating nature: Inspired by disulfide bond formation mechanisms in nature, we demonstrate that polydopamine particles can be used as a promising biomimetic catalyst for the thiol coupling reaction in aqueous media under mild conditions. This approach involves no harmful chemicals and produces no waste products except for water.

Oxidation/reduction interconversion of thiols and disulfides using hydrogen and oxygen catalyzed by a rhodium complex

RhH(PPh3)4 catalyzes reduction of disulfides to thiols by hydrogen and RhH(PPh3)4/1,4- bis(diphenylphosphino)butane (dppb) catalyzes oxidation of thiols to disulfides by oxygen.