304663-40-9

Upstream product

• 111-11-5 methyl octanate 
• 618-36-0 rac-methylbenzylamine 
• 111-64-8 n-octanoic acid chloride 
• 124-07-2 Octanoic acid 

Downstream Products

• 1355027-12-1 N-(1-phenylethyl)undec-1-en-4-amine 
• 149539-14-0 C₁₆H₂₇N 

Relevant academic research and scientific papers

Separation of Enantiomers as Differently Sized Pseudoenantiomeric Salts

Ethylene oligomers terminally functionalized so as to contain a chiral amine are used either alone or in the presence of a structurally and chemically similar low molecular mass antipode to separate a racemic sulfonic acid.

Lipase-catalyzed amidation of carboxylic acid and amines

The amidation reaction is of a very particular interest, especially in the pharmaceutical industry and always requires the activation of the acid with a large excess of reactants. Therefore, a large amount of waste is generated. In order to reduce the environmental impact of such reaction, we have developed enzymatic amidation conditions which are compatible with a wide range of amines and acids, in particular with the biologically relevant lipoic acid. Water is the only by-product generated during this reaction thus a very high atom economy is obtained. In addition, we have shown that the lipase can be recovered and reused several times without a significant loss of activity.

Direct chemoselective allylation of inert amide carbonyls

Direct allylation of inert amide carbonyls utilizing the Schwartz reagent afforded either substituted tertiary or secondary amines. A preactivation step was successfully avoided, which is generally a requisite to increase the electrophilicity of amides. The reaction exhibited remarkable functional group tolerance and proceeded even in the presence of methyl esters and nitro groups.

Acyl transfer catalysis with 1,2,4-Triazole anion

1,2,4-Triazole anion has been identified as an active acyl transfer catalyst suitable for the aminolysis and transesterification of esters.