304678-71-5Relevant academic research and scientific papers
Highly stereoselective and efficient synthesis of functionalized cyclohexanes with multiple stereocenters
Schneider, Christoph,Reese, Oliver
, p. 2585 - 2594 (2007/10/03)
Chiral 7-oxo-2-enimides 2, which were readily obtained through a silyloxy-Cope rearrangement of syn-aldol products 1, have proved to be versatile substrates for a one-step, highly efficient and stereoselective synthesis of functionalized cyclohexanes. Org
Domino Michael aldol and domino Michael Mannich reactions: Highly stereoselective synthesis of functionalized cyclohexanes
Schneider, Christoph,Reese, Oliver
, p. 2948 - 2950 (2007/10/03)
Enantiopure and highly functionalized cyclohexanes may be accessed in a single step and with stereocontrol from the 7-oxo-2-enimides 1 with use of the title reactions (see scheme). The bifunctional substrates 1 are available by a thermal [3.3]-sigmatropic
