304862-50-8Relevant articles and documents
SYNTHESIS AND GROWTH REGULATORY ACTIVITY OF A PROTOTYPE MEMBER OF A NEW FAMILY OF AMlNOTHIOL RADIOPROTECTORS
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Paragraph 0019, (2014/05/07)
The synthesis, growth inhibition and radioprotective activity of the PrC-210 aminothiol, 3-(methyl-amino)-2-((methylamino)methyl)propane-1-thiol, and its polyamine and thiolated polyamine progenitors are reported. All of the molecules significantly inhibi
Synthesis and evaluation of unsymmetrical polyamine derivatives as antitumor agents
Wang, Jianhong,Xie, Songqiang,Li, Yanjie,Guo, Yongjun,Ma, Yuanfang,Zhao, Jin,Phanstiel IV, Otto,Wang, Chaojie
, p. 7005 - 7012 (2008/12/22)
A series of unsymmetrically substituted polyamine derivatives were prepared and their cytotoxicities in mouse leukemia L1210, melanoma B16, and HeLa cells were investigated. The in vitro cytotoxicity revealed that these conjugates could recognize the poly