304876-60-6Relevant academic research and scientific papers
ISOXAZOLINE HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS
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Page/Page column 69-70, (2015/11/10)
This invention pertains generally to compounds of Formula I and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention pertains to methods and compositions for tr
Discovery and characterization of a novel dihydroisoxazole class of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiators
Patel, Nandini C.,Schwarz, Jacob,Hou, Xinjun J.,Hoover, Dennis J.,Xie, Longfei,Fliri, Anton J.,Gallaschun, Randall J.,Lazzaro, John T.,Bryce, Dianne K.,Hoffmann, William E.,Hanks, Ashley N.,McGinnis, Dina,Marr, Eric S.,Gazard, Justin L.,Hajós, Mihály,Scialis, Renato J.,Hurst, Raymond S.,Shaffer, Christopher L.,Pandit, Jayvardhan,O'Donnell, Christopher J.
supporting information, p. 9180 - 9191 (2014/01/06)
Positive allosteric modulators ("potentiators") of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors (AMPAR) enhance excitatory neurotransmission and may improve the cognitive deficits associated with various neurological disorders. Th
