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133059-43-5

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133059-43-5 Usage

Chemical Properties

White powder

Uses

4-Bromo-3-fluorobenzaldehyde is used in preparation of the Deuterated Dihydropyrimidine compound and their application as anti-HBV agent.

Check Digit Verification of cas no

The CAS Registry Mumber 133059-43-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,0,5 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 133059-43:
(8*1)+(7*3)+(6*3)+(5*0)+(4*5)+(3*9)+(2*4)+(1*3)=105
105 % 10 = 5
So 133059-43-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H4BrFO/c8-6-2-1-5(4-10)3-7(6)9/h1-4H

133059-43-5 Well-known Company Product Price

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  • Alfa Aesar

  • (H57833)  4-Bromo-3-fluorobenzaldehyde, 97%   

  • 133059-43-5

  • 250mg

  • 214.0CNY

  • Detail
  • Alfa Aesar

  • (H57833)  4-Bromo-3-fluorobenzaldehyde, 97%   

  • 133059-43-5

  • 1g

  • 659.0CNY

  • Detail
  • Alfa Aesar

  • (H57833)  4-Bromo-3-fluorobenzaldehyde, 97%   

  • 133059-43-5

  • 5g

  • 2967.0CNY

  • Detail

133059-43-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Bromo-3-fluorobenzaldehyde

1.2 Other means of identification

Product number -
Other names 4-bromo-3-fluoro benzaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:133059-43-5 SDS

133059-43-5Related news

Analysis of 4-Bromo-3-fluorobenzaldehyde (cas 133059-43-5) and separation of its regioisomers by one-dimensional and two-dimensional gas chromatography09/02/2019

A starting material, 4-bromo-3-fluorobenzaldehyde, was used for active drug substance (API) AMG 369 production. The presence of the regioisomer impurities in the starting material 4-bromo-3-fluorobenzaldehyde presented significant challenges for the API synthetic route development due to the phy...detailed

133059-43-5Relevant articles and documents

Rhodium-catalyzed reductive carbonylation of aryl iodides to arylaldehydes with syngas

Chen, Suqing,Liu, Zhenghui,Mu, Tiancheng,Wang, Peng,Yan, Zhenzhong,Yu, Dongkun,Zhao, Xinhui

, p. 645 - 656 (2020/05/14)

The reductive carbonylation of aryl iodides to aryl aldehydes possesses broad application prospects. We present an efficient and facile Rh-based catalytic system composed of the commercially available Rh salt RhCl3·3H2O, PPh3 as phosphine ligand, and Et3N as the base, for the synthesis of arylaldehydes via the reductive carbonylation of aryl iodides with CO and H2 under relatively mild conditions with a broad substrate range affording the products in good to excellent yields. Systematic investigations were carried out to study the experimental parameters. We explored the optimal ratio of Rh salt and PPh3 ligand, substrate scope, carbonyl source and hydrogen source, and the reaction mechanism. Particularly, a scaled-up experiment indicated that the catalytic method could find valuable applications in industrial productions. The low gas pressure, cheap ligand and low metal dosage could significantly improve the practicability in both chemical researches and industrial applications.

NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS

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Page/Page column 92; 93, (2010/09/07)

This invention relates to novel compounds which are antagonists or inverse agonists at one or more of the opioid receptors, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy.

REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE A AND B

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Page/Page column 29, (2008/06/13)

The instant invention relates to compounds of formula I, diagrammed below, wherein R3, E, D and Y are defined in the application, which are useful as reversible inhibitors of monoamine oxidase-B and/or monoamine oxidase-A, and therefore useful to treat or prevent neurological diseases or conditions in mammals, preferably humans.

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