304895-28-1

Basic information

• Product Name: N-[5-(4-methoxybenzyl)-1,3-thiazol-2-yl]heptanamide
• Synonyms: N-[5-(4-methoxybenzyl)-1,3-thiazol-2-yl]heptanamide
• CAS NO: 304895-28-1
• Molecular Formula: C18H24N2O2S
• Molecular Weight: 332.46036
• Mol File: 304895-28-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.141±0.06 g/cm3(Predicted)
• PKA: 9.79±0.50(Predicted)
• CAS DataBase Reference: N-[5-(4-methoxybenzyl)-1,3-thiazol-2-yl]heptanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[5-(4-methoxybenzyl)-1,3-thiazol-2-yl]heptanamide(304895-28-1)
• EPA Substance Registry System: N-[5-(4-methoxybenzyl)-1,3-thiazol-2-yl]heptanamide(304895-28-1)

Safety Data

• Hazardous Substances Data: 304895-28-1(Hazardous Substances Data)

Upstream product

• 6281-73-8 heptanoyl-thiourea 
• 807667-27-2 2-chloro-3-(4-methoxyphenyl)propanal 
• 2528-61-2 Heptanoic acid chloride 
• 299953-06-3 5-[(4-methoxyphenyl)methyl]thiazol-2-amine 
• 4346-59-2 para-methoxyphenyldiazonium chloride 

Relevant articles and documents

Heterocyclic syntheses on the basis of arylation products of unsaturated compounds: X. 3-aryl-2-chloropropanals as reagents for the synthesis of 2-amino-1,3-thiazole derivatives

Meerwein reaction of arenediazonium chlorides with acrolein gave 3-aryl-2-chloropropanals which were brought into cyclocondensation with thiourea. The resulting 2-amino-5-benzyl-1,3-thiazoles were acylated with carboxylic acid chlorides and phthalic anhydride to afford, respectively, 2-acylamino-5-benzyl-1,3-thiazoles and N-(5-benzyl-1,3-thiazol-2-yl) phthalimides.