30536-22-2

Upstream product

• 6583-06-8 4-nitro-1,2,3-benzothiadiazole 
• 2274-89-7 5-chloro-4-nito-2,1,3-benzothiadiazole 
• 72023-79-1 5-bromo-4-nitro-benzo[1,2,5]thiadiazole 
• 21110-91-8 5-acetamidobenzo-2,1,3-thiadiazole 
• 874-37-3 benzo[1,2,5]thiadiazol-5-ylamine 
• 16252-88-3 5-nitro-2,1,3-benzothiadiazole 
• 99-56-9 4-Nitrophenylene-1,2-diamine 

Downstream Products

• 1711-66-6 benzo[1,2,5]thiadiazole-4,5-diamine 
• 211-16-5 benzo[1,2-c:3,4-c']bis(1,2,5)thiadiazole 
• 100264-68-4 7,8-diphenyl-[1,2,5]thiadiazolo[3,4-f]quinoxaline 

Relevant academic research and scientific papers

Benzothiadiazole compound and preparation method and use thereof

The present invention relates to a benzothiadiazole compound represented by the following formula I, and a preparation method and use thereof, the benzothiadiazole compound has the biological activityof inhibiting protein-tyrosine-phosphatase SHP2, can be used as a tool compound to study the biological functional relevance of the protein-tyrosine-phosphatase SHP2 in a cell signal transduction process, and provides a new means for prevention and treatment of cancer and metabolic and immune diseases.

Multifunctional Imidazobenzothiadiazole Probe Displaying Solvatofluorochromism and Ability To Form Ion-Pair Complexes in Solid State and in Solution

Fluorescent solid 5-pyridylimidazobenzothiadiazole displays a remarkable solvatofluorochromism and with Zn(AcO)2 and Cd(AcO)2, either in solution or under solvent-free conditions, forms ion-pair complexes that in the solid state can be discriminated and separated by fluorescence measurements and selective extraction with diethyl ether or chloroform. (Chemical Equation Presented).

Synthesis of substituted dipyrido[3,2-a:2′,3′-c]phenazines and a new heterocyclic dipyrido[3,2-f:2′,3′-h]quinoxalino[2,3-b]quinoxaline

Three new α,α′-diimine ligands were synthesized based on condensation of 1,10-phenanthroline-5,6-dione with 1,2-phenylenediamine derivatives using different approaches. All compounds were fully characterized by IR, 1H and 13C NMR, UV-visible, and MS spectroscopies. We report the first example of a dipyrido[3,2-f:2′,3′-h]quinoxalino[2,3-b]quinoxaline, which exhibits a strong absorption at 430 nm and an interesting electrochemical behavior. These new molecules may have biological potential and are of synthetic and technological importance.

Benzo[1,2-c:3,4-c′]bis[1,2,5]selenadiazole, [1,2,5]selenadiazolo-[3, 4-e]-2,1,3-benzothiadiazole, furazanobenzo-2,1,3-thiadiazole, furazanobenzo-2,1,3-selenadiazole and related heterocyclic systems

The first synthesis of benzo[1,2-c:3,4- c′]bis[1,2,5]selenadiazole has been developed starting from commercially available 4-nitrobenzo-2,1,3- selenadiazole. Improved syntheses of the related heterocycles [1,2,5]selenadiazolo[3,4-e]-2,1,3-benzothiadiazole, furazanobenzo-2,1,3- thiadiazole and furazanobenzo-2,1,3-selenadiazole are also reported.