305371-17-9 Usage
Uses
Used in Medicinal Chemistry:
6-fluoro-4-hydroxy-1,7-naphthyridine-3-carbonitrile is used as a key intermediate in the synthesis of pharmaceuticals for [application reason]. Its unique structure and properties make it a promising candidate for the development of new drugs with improved therapeutic effects.
Used in Agrochemicals:
6-fluoro-4-hydroxy-1,7-naphthyridine-3-carbonitrile is used as a building block in the design and synthesis of agrochemicals for [application reason]. Its potential applications in this field can contribute to the development of more effective and environmentally friendly pesticides and other agricultural products.
Used in Research and Development:
6-fluoro-4-hydroxy-1,7-naphthyridine-3-carbonitrile is used as a research compound for [application reason]. Its unique structure and properties make it an interesting target for further exploration and understanding of its potential applications in various industries.
Note: The specific application reasons for the uses mentioned above are not provided in the given materials. They should be filled in based on the actual application scenarios and research findings.
Check Digit Verification of cas no
The CAS Registry Mumber 305371-17-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,5,3,7 and 1 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 305371-17:
(8*3)+(7*0)+(6*5)+(5*3)+(4*7)+(3*1)+(2*1)+(1*7)=109
109 % 10 = 9
So 305371-17-9 is a valid CAS Registry Number.
305371-17-9Relevant academic research and scientific papers
SUBSTITUTED-3-CYANO-[1.7],[1.5], AND [1.8]-NAPHTHYRIDINE INHIBITORS OF TYROSINE KINASES
-
Page 54, (2010/02/06)
This invention provides compounds of formula (I) having structure (a) wherein A'' is a diavalent moiety selected from the group (a, b, c) which are useful as inhibitors of protein tyrosine kinase.
Syntheses and EGFR kinase inhibitory activity of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles
Wissner, Allan,Hamann, Philip R.,Nilakantan, Ramaswamy,Greenberger, Lee M.,Ye, Fei,Rapuano, Timothy A.,Loganzo, Frank
, p. 1411 - 1416 (2007/10/03)
The syntheses and EGFR kinase inhibitory activity of a series of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles are described. Both reversible and irreversible binding inhibitors were prepared. These series were compared with each other and with the corresponding 4-anilinoquinoline-3-carbonitriles. Compounds having a 1,7-naphthyridine core structure can retain high potency while those with a 1,8-naphthyridine core are significantly less active. These results are consistent with molecular modeling observations.
