30557-76-7

Upstream product

• 124601-89-4 (2S,5R)-7,7-dimethyl-6-methylenetricyclo<6,2,1,0^1.5>undecan-2-ol 
• 70591-46-7 (S)-5-methoxycarbonylmethyl-6,6-dimethyl-2-cyclohexen-1-one 
• 119347-50-1 (3aS,5S,7aS)-3-acetoxyethyl-6,6-dimethyl-7-methylene-3-(1-oximinoethyl)-3a,4,5,6,7,7a-hexahydroindene 
• 119347-51-2 Acetic acid 2-((3aR,5S,7aS)-3-acetylamino-6,6-dimethyl-7-methylene-3a,4,5,6,7,7a-hexahydro-1H-inden-5-yl)-ethyl ester 
• 89362-41-4 C₁₆H₂₄O₄ 
• 70591-55-8 4-(2-chloroethyl)-3,3-dimethyl-2-methylidenebicyclo<4.2.0>octan-7-one 
• 119347-45-4 (3S,4aS,6S,7S,8aS)-3-acetoxyethyl-6,7-dihydroxy-2,2,6-trimethyl-1-methylenedecahydronaphthalene 
• 119347-49-8 (3aS,5S,7aS)-3-acetyl-5-acetoxyethyl-6,6-dimethyl-7-methylene-3a,4,5,6,7,7a-hexahydroindene 
• 119347-47-6 (3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane 
• 119347-46-5 (3S,4aS,6RS,7RS,8aS)-3-acetoxyethyl-6,7-epoxy-2,2,6-trimethyl-1-methylene-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene 
• 119347-43-2 (3S,4aS,8aS)-3-acetoxyethyl-2,2,6-trimethyl-1-methylene-1,2,3,4,4a,5,8,8a-octahydronaphthalene 
• 119371-63-0 (3S,4aS,8aS)-2,2,6-trimethyl-1-methylene-1,2,3,4,4a,5,8,8a-octahydronaphthalen-3-ylacetic acid 
• 119347-48-7 (3aR,5S,7aS)-3-acetyl-5-hydroxyethyl-6,6-dimethyl-7-methylene-3a,4,5,6,7,7a-hexahydroindene 
• 119347-52-3 (1RS,5S,8S)-8-hydroxyethyl-7,7-dimethyl-6-methylene-2-indanone 

Downstream Products

• 82463-21-6 12-oxoepizizaene 
• 16203-25-1 (+)-zizanoic acid 
• 16203-25-1 (-)-epizizanoic acid 

Relevant academic research and scientific papers

ASYMMETRIC MICHAEL ADDITION OF A CHIRAL ESTER-DIENOLATE: ENANTIOSELECTIVE SYNTHESIS OF (-)-KHUSIMONE

A double ?-face-selective aprotic Michael addition of the lithium dienolate derived from the chiral senecioate 2b to cyclopentenone coupled with recovery of the auxiliary 14 serves for the enantioselective synthesis of (-)-khusimone 12 (Schemes 1 and 4).

NOVEL METHOD FOR THE SYNTHESIS OF KHUSIMONE

A novel method for synthesis of khusimone, by bringing zizanal into contact with an oxidizing reagent in the presence of a base and an organic solvent.

A NEW SYNTHESIS OF (-)-KHUSIMONE

(-)-Khusimone 1, the minor essential component of vetiver oil with insect repellent activity, was synthesized starting from (S)-6,6-dimethyl-5-methoxycarbonylmethyl-2-cyclohexen-1-one 2.Lewis acid-catalyzed Diels-Alder reaction was employed to obtain the

Total synthesis of zizaane sesquiterpenes: (-)-khusimone, (+)-zizanoic acid, and (-)-epizizanoic acid

Three sesquiterpenes of the zizaane family, khusimone (1), epizizanoic acid (3), and zizanoic acid (2) have been synthesized in optically active form from the ammonium salt of (-)-l-10-camphorsulfonic acid in sixteen, nineteen, and twenty steps respectively.