ASYMMETRIC MICHAEL ADDITION OF A CHIRAL ESTER-DIENOLATE: ENANTIOSELECTIVE SYNTHESIS OF (-)-KHUSIMONE

DOI: 10.1016/S0040-4039(01)99825-9

Source and publish data:

Tetrahedron Letters p. 4975 - 4978 (1983)

Update date:2022-08-25

Topics:

Authors:

Oppolzer, Wolfgang

Pitteloud, Rita

Bernardinelli, Gerald

Baettig, Kurt

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Article abstract of DOI:10.1016/S0040-4039(01)99825-9

A double ?-face-selective aprotic Michael addition of the lithium dienolate derived from the chiral senecioate 2b to cyclopentenone coupled with recovery of the auxiliary 14 serves for the enantioselective synthesis of (-)-khusimone 12 (Schemes 1 and 4).

Full text of DOI:10.1016/S0040-4039(01)99825-9

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