305811-22-7Relevant academic research and scientific papers
Metal-free chemoselective reduction of nitroaromatics to anilines via hydrogen transfer strategy
Shuai, Qi,Li, Jun,Zhao, Feng,Su, Weike,Deng, Guojun
, p. 965 - 975 (2019/04/13)
A novel protocol for chemoselective reduction of aromatic nitro compounds to aromatic amines has been established. The metal-free reduction goes through a hydrogen transfer process. Various easily reducible functional groups can be well tolerated under the optimized reaction conditions.
Imidazoline derivatives as alpha-1A adrenoceptor ligands
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Page/Page column 26, (2010/02/11)
Compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed. Such compounds are useful in the treatment of Alpha-1A mediated diseases or conditions such as urinary incontinence.
2-(anilinomethyl)imidazolines as alpha1A adrenergic receptor agonists: 2'-heteroaryl and 2'-oxime ether series.
Navas 3rd., Frank,Bishop, Michael J,Garrison, Deanna T,Hodson, Stephen J,Speake, Jason D,Bigham, Eric C,Drewry, David H,Saussy, David L,Liacos, James H,Irving, Paul E,Gobel, M Jeffrey
, p. 575 - 579 (2007/10/03)
A series of 2'-heteroaryl and 2'-oxime anilinomethylimidazolines was prepared and evaluated in in vitro functional assays for cloned human alpha1A, alpha1B, and alpha1D receptor subtypes. Potent and selective alpha1A agonists have been identified in these series.
Derivatives of Phenylurea as Antagonists of Mice, Rat, Guinea Pig, and Rabbit 5-HT3 Receptors
Hansen, John Bondo,Christensen, Birgitte,Weiss, Jan,Suzdak, Peter D.,Sheardown, Malcolm J.,et al.
, p. 308 - 315 (2007/10/03)
1,2,4-Oxadiazolyl- and O-alkyloximinomethyl-substituted phenylureas equipotently bind to 5-HT3 receptors from different species in vitro in contrast to the normal 10-100 fold lower affinity for guinea pig ileal receptors. Compared to the in vitro receptor
