305820-01-3Relevant academic research and scientific papers
Efficient synthesis of 2'-deoxynucleoside 3'-C-phosphonates: Reactivity of geminal hydroxyphosphonate moiety
Kralikova,Budesinsky,Masojidkova,Rosenberg
, p. 1159 - 1183 (2007/10/03)
In this report we present a novel, simple way for the synthesis of 3'-C-phosphonate derivatives of all four basic 2'-deoxynucleosides in both fully protected and deprotected forms. The reactivity of the geminal hydroxy phosphonate moiety located at the 3'
