305834-38-2Relevant articles and documents
Synthesis and evaluation of18F-labeled 2-phenylbenzothiazoles as positron emission tomography imaging agents for amyloid plaques in alzheimer's disease
Serdons, Kim,Terwinghe, Christelle,Vermaelen, Peter,Van Laere, Koen,Kung, Hank,Mortelmans, Luc,Bormans, Guy,Verbruggen, Alfons
supporting information; experimental part, p. 1428 - 1437 (2009/12/26)
Imaging agents targeting amyloid β(Aβ) may be useful for early diagnosis and follow-up of treatment of patients with Alzheimer's disease (AD). Three of five tested 2-(4′-fluorophenyl)-1,3-benzothiazoles displayed high binding affinities for Aβ plaques in
Benzothiazole-4,7-diones and benzoxazole-4,7-diones with substituents in position 5 or 6 and method for production thereof
-
Page/Page column 23, (2010/11/08)
A subject of the invention is a selective process for the preparation of derivatives of benzothiazole-4,7-diones and benzoxazole-4,7-diones monosubstituted in position 5 or in position 6 by an amino group itself optionally substituted. Said derivatives ar