305834-49-5Relevant academic research and scientific papers
A convenient method for the synthesis of 3,5,7-trimethoxy-2-phenyl-4-quinolones
Beney,Hadjeri,Mariotte,Boumendjel
, p. 7037 - 7039 (2007/10/03)
The synthesis of 2-aryl-3,5,7-trimethoxy-4-quinolones was accomplished in three steps starting from 3,5-dimethoxyaniline and an aroyl chloride. These structures might be used as potential flavonol analogs. (C) 2000 Elsevier Science Ltd.
Synthesis and topoisomerase inhibitory activities of novel aza-analogues of flavones
Sui, Zhihua,Nguyen, Van N.,Altom, Jason,Fernandez, Jeffrey,Hilliard, Jamese J.,Bernstein, Jeffrey I.,Barrett, John F.,Ohemeng, Kwasi A
, p. 381 - 387 (2007/10/03)
A series of aza-flavones (3-hydroxy-2-phenyl-4-quinolones) were designed and synthesized as inhibitors of bacterial DNA-gyrase and mammalian topoisomerase II. Structure activity relationships of the compounds against each of the enzymes are discussed.
