305836-78-6

Basic information

• Product Name: (2S)-1-(4-methylphenylsulfonyl)-1,2,3,6-tetrahydropyridine-2-carboxylic acid
• Synonyms: (2S)-1-(4-methylphenylsulfonyl)-1,2,3,6-tetrahydropyridine-2-carboxylic acid
• CAS NO: 305836-78-6
• Molecular Weight: 281.332
• Mol File: 305836-78-6.mol

Chemical Properties

• CAS DataBase Reference: (2S)-1-(4-methylphenylsulfonyl)-1,2,3,6-tetrahydropyridine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-1-(4-methylphenylsulfonyl)-1,2,3,6-tetrahydropyridine-2-carboxylic acid(305836-78-6)
• EPA Substance Registry System: (2S)-1-(4-methylphenylsulfonyl)-1,2,3,6-tetrahydropyridine-2-carboxylic acid(305836-78-6)

Safety Data

• Hazardous Substances Data: 305836-78-6(Hazardous Substances Data)

Upstream product

• 115344-32-6 (2S)-N-(1-benzyloxymethyl-3-hydroxypropyl)-4-methylbenzenesulfonamide 
• 919116-88-4 N-[1-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-methyl-benzenesulfonamide 
• 919116-89-5 N-allyl-N-(1-benzyloxymethyl-3-hydroxy-propyl)-4-methyl-benzenesulfonamide 
• 919116-86-2 (2S)-N-allyl-N-(1-benzyloxymethyl-but-3-enyl)-4-methyl-benzenesulfonamide 
• 905859-22-5 4-benzyloxymethyl-3-(toluene-4-sulfonyl)-[1,3]oxazinan-6-one 
• 919116-87-3 (2S)-2-benzyloxymethyl-1-(4-methylphenylsulfonyl)-1,2,3,6-tetrahydropyridine 
• 919116-85-1 (2S)-N-allyl-N-[1-benzyloxymethyl-3-(t-butyldimethylsilanyloxy)propyl]-4-methylbenzenesulfonamide 
• 919116-90-8 N-allyl-N-(1-benzyloxymethyl-3-oxopropyl)-4-methylbenzenesulfonamide 
• 919116-91-9 [1-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-pyridin-2-yl]-methanol 
• 76472-92-9 1,2,3,6-tetrahydropyridine-2-carboxylic acid hydrochloride 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 31456-71-0 (2S)-1,2,3,6-tetrahydropyridine-2-carboxylic acid 

Relevant articles and documents

Synthesis of pipecolic acid and baikiain

A straightforward synthesis of pipecolic acid and baikiain was achieved from trans-(2S,4R)-4-hydroxyproline via the key steps of regioselective Baeyer-Villiger reaction. and ring-closing metathesis.

A new soluble polymer-supported sulfonyl linker - Application to the synthesis of cyclic α-amino acids

A new soluble poly(ethylene glycol)-supported protecting group of the SES (silylethylsulfonyl) type has been prepared and utilized in the synthesis of cyclic amino esters by ring-closing metathesis (RCM). Acidic cleavage from the support was performed to recover the fully deprotected amino acids. More conventional deprotection conditions with fluoride anions resulted in aromatization of the heterocycles in the case of the 6-membered ring and provided a new route to the synthesis of substituted pyridines. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.