305838-49-7

Upstream product

• 107-30-2 chloromethyl methyl ether 
• 150779-88-7 (2S,3S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester 
• 114301-34-7 (2S,3S)-2-amino-N-<(tert-butyloxy)carbonyl>-1,3-dihydroxy-1,2-O,N-isopropylidene-4-pentene 
• 1339950-32-1 tert-butyl (5S,6S)-6-[(tert-butyldiphenylsilyloxy)methyl]-5-(methoxymethoxy)-5,6-dihydropyridine-1(2H)-carboxylate 
• 1339950-30-9 tert-butyl N-allyl-N-[(5S,6S)-10,10-dimethyl-9,9-diphenyl-5-vinyl-2,4,8-trioxa-9-silaundecan-6-yl]carbamate 
• 1339950-28-5 tert-butyl N-[(5S,6S)-10,10-dimethyl-9,9-diphenyl-5-vinyl-2,4,8-trioxa-9-silaundecan-6-yl]carbamate 
• 1042338-92-0 (1S,2S)-(1-hydroxymethyl-2-methoxymethoxy-but-3-enyl)-carbamic acid tert-butyl ester 
• 1042338-78-2 (1S,4S)-4-(1-methoxymethoxyallyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 305838-43-1 (2S,3R)-3-hydroxy-2-(hydroxymethyl)piperidine-1-carboxylic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 305838-42-0 (2S,3R)-1-(tert-butyldimethylsilanyloxy)-2-dibenzylamino-5-[1,3]dioxolan-2-yl-pentan-3-ol 
• 305838-48-6 2-(tert-butyl-diphenyl-silanyloxymethyl)-3-oxo-piperidine-1-carboxylic acid tert-butyl ester 
• 531504-63-9 (2S,3R)-2-Hydroxymethyl-piperidin-3-ol; hydrochloride 

Downstream Products

• 119593-44-1 (2R,3S)-3-hydroxypipecolic acid 

Relevant academic research and scientific papers

A stereoselective route to cis-(2S,3R)-3-hydroxypipecolic acid and two enantiomeric cis-2-hydroxymethyl-3-hydroxypiperidine derivatives

Stereoselective routes to cis-(2S,3R)-3-hydroxypipecolic acid and two enantiomeric cis-2-hydroxymethyl-3-hydroxypiperidine derivatives from a common precursor have been developed, which featured stereocontrolled vinylation of a -chiral aldehyde and ring-closing metathesis as key steps. Georg Thieme Verlag Stuttgart. New York.

An efficient stereoselective and stereodivergent synthesis of (2R,3R)- and (2R,3S)-3-hydroxypipecolic acids

Asymmetric syntheses of (2R,3R) and (2R,3S)-3-hydroxypipecolic acids are reported featuring a key diastereoselective addition of Buchi's Grignard reagent to the chiral serinal L-5. Based on conformational analysis, a stereocontrolled reduction of piperidi