305838-42-0

Basic information

• Product Name: (2S,3R)-1-(tert-butyldimethylsilanyloxy)-2-dibenzylamino-5-[1,3]dioxolan-2-yl-pentan-3-ol
• Synonyms: (2S,3R)-1-(tert-butyldimethylsilanyloxy)-2-dibenzylamino-5-[1,3]dioxolan-2-yl-pentan-3-ol
• CAS NO: 305838-42-0
• Molecular Weight: 485.739
• Mol File: 305838-42-0.mol

Chemical Properties

• CAS DataBase Reference: (2S,3R)-1-(tert-butyldimethylsilanyloxy)-2-dibenzylamino-5-[1,3]dioxolan-2-yl-pentan-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-1-(tert-butyldimethylsilanyloxy)-2-dibenzylamino-5-[1,3]dioxolan-2-yl-pentan-3-ol(305838-42-0)
• EPA Substance Registry System: (2S,3R)-1-(tert-butyldimethylsilanyloxy)-2-dibenzylamino-5-[1,3]dioxolan-2-yl-pentan-3-ol(305838-42-0)

Safety Data

• Hazardous Substances Data: 305838-42-0(Hazardous Substances Data)

Upstream product

• 239437-14-0 N,N-dibenzyl-O-tert-butyldimethylsilyl serinol 
• 18742-02-4 2-bromo-2-(2-ethyl)dioxolane 
• 125654-82-2 (S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-dibenzylamino-propionaldehyde 

Downstream Products

• 305838-46-4 Dibenzyl-[(1S,2R)-1-(tert-butyl-dimethyl-silanyloxymethyl)-4-[1,3]dioxolan-2-yl-2-methoxymethoxy-butyl]-amine 
• 305838-49-7 tert-butyl (2S,3S)-2-[(tert-butyldiphenylsilyloxy)methyl]-3-(methoxymethoxy)piperidine-1-carboxylate 
• 305838-44-2 2-(tert-butyl-diphenyl-silanyloxymethyl)-3-methoxymethoxy-piperidine-1-carboxylic acid tert-butyl ester 
• 305838-48-6 2-(tert-butyl-diphenyl-silanyloxymethyl)-3-oxo-piperidine-1-carboxylic acid tert-butyl ester 
• 150779-88-7 (2S,3S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester 
• 119593-44-1 (2R,3S)-3-hydroxypipecolic acid 
• 349555-97-1 (4R,5S)-4-Benzyloxy-5-dibenzylamino-6-hydroxy-hexanal 
• 349556-03-2 (2S,3R)-1-(tert-butyldimethylsilanyloxy)-3-benzyloxy-2-dibenzylaminooctadecane-1,6-diol 
• 349556-00-9 (2S,3R)-1-(tert-butyldimethylsilanyloxy)-3-benzyloxy-2-dibenzylamino-6-oxooctadecan-6-one 
• 349556-02-1 (4R,5S)-6-(tert-butyldimethylsilanyloxy)-4-benzyloxy-5-dibenzylaminohexanal 
• 849428-89-3 (2S,3R,6S)-(3-benzyloxy-6-dodecylpiperidin-2-yl)methanol 
• 14058-54-9 (-)-deoxoprosophylline 
• 849428-90-6 (2S,3R)-3-benzyloxy-2-dibenzylamino[1,3]dioxolan-6-yl-octadecan-1-ol 
• 849428-92-8 [(1S,2R)-2-Benzyloxy-4-(2-dodecyl-[1,3]dioxolan-2-yl)-1-hydroxymethyl-butyl]-carbamic acid benzyl ester 

Relevant articles and documents

Asymmetric total synthesis of (-)-deoxoprosophylline

Asymmetric syntheses of (-)-deoxoprosophylline from chiral L-N,N-dibenzyl serine (TBDMS) aldehyde is reported. A highly diastereoselective intramolecular reductive amination of ω-oxo amino diol is a key step of the present synthesis.

A short synthesis of (-)-deoxoprosophylline

Syntheses of (-)-deoxoprosophylline from chiral L-N,N-dibenzylserine (TBDMS) aldehyde is reported. A highly diastereoselective nucleophilic addition of Buechi's Grignard reagent to chiral serinal followed by an intramolecular reductive amination of ω-oxo

An efficient stereoselective and stereodivergent synthesis of (2R,3R)- and (2R,3S)-3-hydroxypipecolic acids

Asymmetric syntheses of (2R,3R) and (2R,3S)-3-hydroxypipecolic acids are reported featuring a key diastereoselective addition of Buchi's Grignard reagent to the chiral serinal L-5. Based on conformational analysis, a stereocontrolled reduction of piperidi