30590-60-4

Basic information

• Product Name: 2,2,7-trimethyl-2,3-dihydro-1-benzofuran
• Synonyms: Benzofuran, 2,3-dihydro-2,2,7-trimethyl-; Benzofuran, 2,3-dihydro-2,2,7-trimethyl-,
• CAS NO: 30590-60-4
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.2283
• Mol File: 30590-60-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 218.1°C at 760 mmHg
• Flash Point: 78.3°C
• Density: 0.987g/cm³
• Vapor Pressure: 0.189mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: 2,2,7-trimethyl-2,3-dihydro-1-benzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,7-trimethyl-2,3-dihydro-1-benzofuran(30590-60-4)
• EPA Substance Registry System: 2,2,7-trimethyl-2,3-dihydro-1-benzofuran(30590-60-4)

Safety Data

• Hazardous Substances Data: 30590-60-4(Hazardous Substances Data)

Usage

General Description

2,2,7-trimethyl-2,3-dihydro-1-benzofuran, also known as exaltolide, is a synthetic musk fragrance often used in perfumes and personal care products. It is a clear, colorless liquid with a sweet, floral odor reminiscent of lily of the valley. Exaltolide is considered a low-to-moderate skin irritant and has been known to cause allergic reactions in some individuals. It is also known for its ability to linger on the skin and clothing for long periods of time. Despite its widespread use, there are concerns about potential health risks associated with prolonged exposure to exaltolide, and some researchers have suggested that it may be a potential endocrine disruptor.

Upstream product

• 66128-97-0 1-methyl-2-(2-methylallyloxy)benzene 
• 628-13-7 pyridine hydrochloride 
• 91969-39-0 2-Hydroxy-1-methyl-3-methallyl-benzol 
• 30088-16-5 2-Hydroxy-1-methyl-3-(2-methyl-propenyl)-benzol 
• 7487-88-9 magnesium sulfate 
• 824-42-0 2-methoxy-3-methylbenzaldehyde 
• 96126-90-8 2-(1-Hydroxy-2-methyl-propyl)-6-methyl-phenol 

Downstream Products

• 1243545-28-9 2,2,7-trimethyl-6-(4-methylphenyl)-2,3-dihydro-1-benzofuran 

Relevant articles and documents

Benzofuran derivatives

The present invention provides a compound represented by the following formula (I): wherein: Ring A represents an optionally substituted piperazine ring, an optionally substituted morpholine ring, or an optionally substituted homopiperazine ring;R1 and R2 are the same or different from each other, and represent a hydrogen atom or optionally substituted lower alkyl;R3 and R4 are the same or different from each other, and represent a hydrogen atom or halogenated or non-halogenated lower alkyl;R5 to R7 are the same or different from each other, and represent a hydrogen atom, hydroxy, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkoxy, optionally substituted cycloalkyl, optionally substituted aryl, an optionally substituted aromatic heterocyclic ring, optionally substituted amino, or acyl; and represents a single bond or double bond, or a salt thereof.

Mo(CO)6 catalyzed one-pot conversion of allyl aryl ethers to dihydrobenzofurans

Molybdenum hexacarbonyl effectively catalyses a tandem Claisen rearrangement-cyclization reaction of allyl aryl ethers to give good yields of dihydrobenzofurans.

ONE-POT SYNTHESES OF 2,3-DIHYDRO-2,2-DIMETHYLBENZOFURAN DERIVATIVES

A tandem Claisen rearrangement-cyclization reaction of aryl methallyl ethers afforded the corresponding 2,3-dihydro-2,2-dimethylbenzofuran derivatives at -70 deg C with aluminium chloride.