306281-86-7 Usage
Uses
Used in Pharmaceutical Synthesis:
(R)-2-Amino-2-(4-trifluoromethylphenyl)ethanol is used as an intermediate in the synthesis of various drugs, particularly in the development of antipsychotic and antihistamine medications. Its unique structure and functional groups make it a valuable component in creating these therapeutic agents.
Used in Disease and Disorder Treatment:
(R)-2-Amino-2-(4-trifluoromethylphenyl)ethanol has also been investigated for its potential use in the treatment of various diseases and disorders. Its specific stereochemistry and functional groups may contribute to its effectiveness in targeting specific biological pathways or receptors, offering new avenues for therapeutic intervention.
Check Digit Verification of cas no
The CAS Registry Mumber 306281-86-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,6,2,8 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 306281-86:
(8*3)+(7*0)+(6*6)+(5*2)+(4*8)+(3*1)+(2*8)+(1*6)=127
127 % 10 = 7
So 306281-86-7 is a valid CAS Registry Number.
InChI:InChI=1S/C9H10F3NO/c10-9(11,12)7-3-1-6(2-4-7)8(13)5-14/h1-4,8,14H,5,13H2/t8-/m0/s1
306281-86-7Relevant academic research and scientific papers
Enantioselective complexation of phenolic crown ethers with chiral aminoethanol derivatives: Effects of substituents of aromatic rings of hosts and guests on complexation
Hirose, Keiji,Ogasahara, Kazuko,Nishioka, Kazuyuki,Tobe, Yoshito,Naemura, Koichiro
, p. 1984 - 1993 (2007/10/03)
Optically active azophenolic crown ethers having phenyl groups substituted at the respective para-position were prepared and their association constants with chiral aminoethanol derivatives, including 2-amino-2-phenyl-ethanols having an electron-donating or an electron-withdrawing group, were determined in chloroform by means of UV-vis titration methods. The enantioselectivities of these crown ethers are estimated from the ratio of the association constants KR/KS and the effect of aromatic substituents of both hosts and guests on the binding abilities and enantioselectivities is discussed. The structures of the complexes were investigated on the basis of the 1H NMR and UV-vis spectra.
