306296-84-4

Upstream product

• 74879-18-8 (S)-2-methylpiperazine 
• 90-99-3 diphenylchloromethane 

Downstream Products

• 1009304-83-9 (S)-tert-butyl 2-(4-benzhydryl-2-methylpiperazin-1-yl)acetate 
• 1009304-82-8 (S)-tert-butyl 2-(4-benzhydryl-3-methylpiperazin-1-yl)acetate 
• 306296-85-5 C₂₇H₃₅N₃O₂ 

Relevant academic research and scientific papers

Glycine transporter-1 inhibitors

The present invention provides compounds that are glycine transporter 1 (hereinafter referred to as GlyT-1) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of GlyT1 such as cognitive disorders associated with Schizophrenia, ADHD (attention deficit hyperactivity disorder), MCI (mild cognitive impairment), and the like. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

PIPERAZINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS

The use is described of CCR5 antagonists of formula (I) or a pharmaceutically acceptable salt thereof, wherein: R is optionally substituted phenyl, pyridyl, thiophenyl or naphthyl; R 1 is hydrogen or alkyl; R 2 is substituted phenyl, substituted heteroary

Piperazine derivatives useful as CCR5 antagonists

The use of CCR5 antagonists of the formula or a pharmaceutically acceptable salt thereof, wherein R is optionally substituted phenyl, pyridyl, thiophenyl or naphthyl; R1is hydrogen or alkyl; R2is substituted phenyl, substituted heter