30651-03-7Relevant academic research and scientific papers
Efficient preparation of apically substituted diamondoid derivatives
Kahl, Paul,Tkachenko, Boryslav A.,Novikovsky, Anatoliy A.,Becker, Jonathan,Dahl, Jeremy E. P.,Carlson, Robert M. K.,Fokin, Andrey A.,Schreiner, Peter R.
, p. 787 - 798 (2014/04/03)
We present an effective three-step chromatography-free sequence for the preparation of apical monohydroxy derivatives of diamantane, triamantane, and [121]tetramantane from the corresponding bis-apical diols utilizing tert-butyldimethylsilyl chloride as t
Selective hydroxylation of adamantane and its derivatives
Khusnutdinov,Shchadneva,Mukhametshina,Dzhemilev
scheme or table, p. 1137 - 1142 (2009/12/03)
A general method was developed for hydroxylation into the nodal position of adamantane and its 1- and 2-substituted derivatives employing systems H 2O-CBr4 (BrCCl3, CCl4) in the presence of complexes of Pd, Ni, Ru, Co, Mo, W, and Fe. The oxidants in the systems are hypochlorous (HOCl) or hypobromous (HOBr) acids generated from water and halomethanes under the reaction conditions.
Hydroxy derivatives of diamantane, triamantane, and [121]tetramantane: Selective preparation of bis-apical derivatives
Fokina, Natalie A.,Tkachenko, Boryslav A.,Merz, Anika,Serafin, Michael,Dahl, Jeremy E. P.,Carlson, Robert M. K.,Fokin, Andrey A.,Schreiner, Peter R.
, p. 4738 - 4745 (2008/03/13)
Functionalizations of diamantane, triamantane, and tetramantane with electrophihc reagents (Br2, nitric acid) lead to various apical and medial disubstituted products that were separated and characterized individually. The highly desirable and otherwise inaccessible thermodynamically more stable apical bis-derivatives were obtained with high preparative yields through acid catalyzed isomerizations. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
Diamondoid derivatives possessing therapeutic activity in the treatment of neurologic disorders
-
Page/Page column 20-23, (2008/06/13)
This invention relates to diamondoid derivatives which exhibit therapeutic activity. Specifically, the diamondoid derivatives herein exhibit therapeutic effects in the treatment of neurologic disorders. Also provided are methods of treatment, prevention a
Functionalized nanodiamonds part I. An experimental assessment of diamantane and computational predictions for higher diamondoids
Fokin, Andrey A.,Tkachenko, Boryslav A.,Gunchenko, Pavel A.,Gusev, Dmitriy V.,Schreiner, Peter R.
, p. 7091 - 7101 (2007/10/03)
The structures, strain energies, and enthalpies of formation of diamantane 1, triamantane 2, isomeric tetramantanes 3-5, Td-pentamantane 6, and D3dhexamantane 7, and the structures of their respective radicals, cations, as well as ra
REACTION OF HYDROXYDIAMANTANES WITH CHLOROETHYLENES IN SULFURIC ACID
Vodicka, Ludek,Burkhard, Jiri,Janku, Josef
, p. 1086 - 1093 (2007/10/02)
Reaction of hydroxydiamantanes with 1,1-dichloroethylene in concentrated sulfuric acid leads to complex reaction mixtures, containing predominantly diamantylacetic and diamantanebisacetic acids.The same reaction with trichloroethylene affords diamantylchloroacetic and diamantanebischloroacetic acids.In all these products the substituents are bonded to the apical and secondary carbon atoms of the diamantane skeleton.For steric reasons, acids with carboxyl in the medial position are not formed.
Thermochemistry of Bridged-ring Substances. Enthalpies of Formation of Diamantan-1-, -3-, and -4-ol and of Diamantanone
Clark, Timothy,Knox, Trevor McO.,McKervey, M. Anthony,Mackle, Henry
, p. 1686 - 1689 (2007/10/02)
The enthalpies of combustion and of sublimation four mono-oxygenated diamantanes have been determined.The derived solid and gas-phase enthalpies of formation in kcal mol-1 at 298.15 K follow: diamantanone, -81.16+/-0.38, -56.53+/-0.41; diamantan-1-ol, -102.49+/-0.24, -74.30+/-0.28; diamantan-3-ol, -98.89+/-0.35, -71.14+/-1.10; diamantan-4-ol, -103.96+/-0.39, -75.80+/-0.39.Oxo and hydroxy group increments within the diamantane, adamantane, and cyclohexane series are discussed.Enthalpy differences betveen the isomeric diamantanols are compared with existing data from equilibration studies in solution.Comparisons are made between the experimental gas-phase enthalpies of formation and those obtained by molecular mechanics (empirical force field) calculations based on the Allinger MM1 force field model.
SOME COMMENTS ON THE THERMAL STABILITY OF SUBSTITUTED AMMONIUM, PHOSPHONIUM, AND ARSONIUM PERMANGANATES AND THEIR USE IN ALKANE OXIDATION
Leddy, Bernard P.,McKervey, M.Antony,McSweeney, Peter
, p. 2261 - 2264 (2007/10/02)
Tetraethyl- and tetrabutylammonium permanganate are less prone to explosive decomposition when heated than are benzyl(triethyl)ammonium and methyl(triphenyl)phosphonium permanganate and are about equally effective as oxidants for the conversion of alkanes into alcohol and ketones.
