30672-70-9 Usage
Uses
Used in Pharmaceutical Synthesis:
2-fluorosulphonylbenzenesulphonyl chloride is utilized as a key intermediate in the synthesis of pharmaceuticals, due to its ability to introduce sulfonyl fluoride groups into various organic molecules, enhancing the reactivity and properties of the final drug compounds.
Used in Agrochemical Production:
In the agrochemical industry, 2-fluorosulphonylbenzenesulphonyl chloride serves as a precursor to active ingredients in pesticides and herbicides, contributing to the development of more effective and targeted crop protection agents.
Used in Dye Manufacturing:
2-fluorosulphonylbenzenesulphonyl chloride is also employed in the production of dyes, where its reactivity allows for the creation of a wide range of colorants used in various industries, including textiles and printing.
Used as a Reagent in Organic Synthesis:
2-fluorosulphonylbenzenesulphonyl chloride functions as a reagent in organic synthesis, facilitating specific chemical reactions that are otherwise difficult to achieve, thus expanding the scope of synthetic organic chemistry.
Used in the Synthesis of Other Important Chemicals:
Beyond its direct applications, 2-fluorosulphonylbenzenesulphonyl chloride also acts as a precursor to other significant chemicals, further highlighting its versatility and importance in the chemical industry.
Given the high reactivity and corrosiveness of 2-fluorosulphonylbenzenesulphonyl chloride, it is imperative that it is handled with extreme care and under proper safety conditions in a controlled laboratory environment to prevent accidents and ensure the safety of personnel and equipment.
Check Digit Verification of cas no
The CAS Registry Mumber 30672-70-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,6,7 and 2 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 30672-70:
(7*3)+(6*0)+(5*6)+(4*7)+(3*2)+(2*7)+(1*0)=99
99 % 10 = 9
So 30672-70-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H4ClFO4S2/c7-13(9,10)5-3-1-2-4-6(5)14(8,11)12/h1-4H
30672-70-9Relevant academic research and scientific papers
(Chlorosulfonyl)benzenesulfonyl Fluorides - Versatile Building Blocks for Combinatorial Chemistry: Design, Synthesis and Evaluation of a Covalent Inhibitor Library
Tolmachova, Kateryna A.,Moroz, Yurii S.,Konovets, Angelika,Platonov, Maxim O.,Vasylchenko, Oleksandr V.,Borysko, Petro,Zozulya, Sergey,Gryniukova, Anastasia,Bogolubsky, Andrey V.,Pipko, Sergey,Mykhailiuk, Pavel K.,Brovarets, Volodymyr S.,Grygorenko, Oleksandr O.
, p. 672 - 680 (2018/11/23)
Multigram synthesis of (chlorosulfonyl)benzenesulfonyl fluorides is described. Selective modification of these building blocks at the sulfonyl chloride function under parallel synthesis conditions is achieved. It is shown that the reaction scope includes the use of (hetero)aromatic and electron-poor aliphatic amines (e.g., amino nitriles). Utility of the method is demonstrated by preparation of the sulfonyl fluoride library for potential use as covalent fragments, which is demonstrated by a combination of in silico and in vitro screening against trypsin as a model enzyme. As a result, several inhibitors were identified with activity on par with that of the known inhibitor.
