306732-27-4Relevant academic research and scientific papers
Sustainable Synthesis of Oximes, Hydrazones, and Thiosemicarbazones under Mild Organocatalyzed Reaction Conditions
Morales, Sara,Ace?a, José Luis,García Ruano, José Luis,Cid, M. Belén
, p. 10016 - 10022 (2016/11/02)
Pyrrolidine catalyzes very efficiently, presumably via iminium activation, the formation of acyloximes, acylhydrazones, and thiosemicarbazones derived from aromatic and aliphatic aldehydes using equimolar amounts of reagents and green solvents. Experimental simplicity and excellent yields after a simple filtration are the main advantages of the method, being an alternative to those currently available especially for the acyl derivatives, which do not work under uncatalyzed conditions. Its application to the synthesis of acyloximes by direct condensation between aldehydes and acylhydroxylamines is unprecedented.
A novel synthesis of carboxylic acid oxime esters catalyzed by 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
Shi, Wei,Zhang, Jiming,Zhou, Qin,Wang, Xingjian,Qi, Xiaowei,Guo, Lianyong,Ma, Wanyong,Zhou, Jianhua
, p. 7125 - 7128 (2015/04/22)
We describe a facile synthesis of carboxylic acid oxime esters in acetonitrile from the corresponding carboxylic acids and oximes catalyzed by 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate in the presence of triethylamine at room temperature under mild conditions.
