306747-98-8

Basic information

• Product Name: 1H-Pyrazole-4-methanamine, N-ethyl-3,5-dimethyl-
• Synonyms: 1H-Pyrazole-4-methanamine, N-ethyl-3,5-dimethyl-
• CAS NO: 306747-98-8
• Molecular Formula: C8H15N3
• Molecular Weight: 153.22
• Mol File: 306747-98-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 289.1±35.0 °C(Predicted)
• Appearance: /
• Density: 1.010±0.06 g/cm3(Predicted)
• PKA: 16.15±0.50(Predicted)
• CAS DataBase Reference: 1H-Pyrazole-4-methanamine, N-ethyl-3,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-4-methanamine, N-ethyl-3,5-dimethyl-(306747-98-8)
• EPA Substance Registry System: 1H-Pyrazole-4-methanamine, N-ethyl-3,5-dimethyl-(306747-98-8)

Safety Data

• Hazardous Substances Data: 306747-98-8(Hazardous Substances Data)

Upstream product

• 75-04-7 ethylamine 
• 91979-38-3 1-chloromethyl-3,5-dimethyl-1H-pyrazole hydrochloride 
• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 50-00-0 formaldehyd 

Relevant articles and documents

Synthesis and reactivity of 3,5-dimethyl-4-aminomethylpyrazole ligands. An entry to new water-soluble pyrazolate rhodium(I) complexes

The new pyrazoles 3,5-dimethyl-4-(ethylamino)methylpyrazole (HL1) and 3,5-dimethyl-4-(isopropylamino)methylpyrazole (HL2), both containing aminoalkyl groups at position 4 have been prepared by aminoalkylation of 3,5-dimethylpyrazole and by the reaction between 1-chloromethyl-3,5-dimethylpyrazolium chloride and NH2R amines. The reaction between HL1, HL2 and [RhCl(COD)]2 resulted in complexes of formula [Rh2(HL1)2(COD)2]Cl2 (1) and [Rh2(HL2)2(COD)2]Cl2 (2), which contained the pyrazole ligands in the 'zwitterionic' pyrazolate-ammonium forms. The X-ray structure analysis of 2 confirmed the neutral nature of bridging-pyrazolate ligands and revealed that 1 and 2 belonged to the [Rh2(Pz)2L2] family of compounds. The same reaction with two equivalents of NaOMe resulted in neutral pyrazolate complexes [Rh2(L1)2(COD)2] (5) and [Rh2(L2)2(COD)2] (6). The reaction between both cationic and neutral pyrazolate complexes and a 1:1 CO-H2 mixture (20 atm) led to the dinuclear pyrazolate-bridged tetracarbonyl compounds 3, 4, 7 and 8 in good yields. Tetracarbonyl complexes 3 and 4 were not isolated in pure state. All the complexes synthesized are soluble in polar solvents such as water.