30690-43-8Relevant academic research and scientific papers
Dibenzothiazepinthione as antiviral agents
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, (2008/06/13)
Compounds of formula (I) wherein n is 0, 1 or 2; and R1 and R2, which may be the same or different, each represent one or more ring substituent(s) selected from: hydroxy, halogen, cyano, nitro, C1-6 alkyl, C3-6 cycloalkyl or C1-6 alkoxy (where the alkyl or cycloalkyl moiety may be optionally substituted by one or more substituents selected from halogen atoms and hydroxyl groups); --NR4 R5 where R4 and R5 which may be the same or different, each represent hydrogen or C1-6 are each as defined above; phenyl, phenyl C1-3 alkoxy or phenyl C1-3 alkyl where the phenyl group may be optionally substituted by one or more substituents independently selected from C1-6 alkyl, C1-6 alkoxy, hydroxy, nitro, halogen and amino; and --CO2 H or --COR7 where R7 is C1-6 alkyl or C3-6 cycloalkyl; R3 is hydrogen or C1-4 alkyl: and esters, salts and other physiologically functional derivatives thereof, show activity as antiviral agents, for example against HIV. The majority of the compounds are novel.
