306960-22-5

Upstream product

• 59896-02-5 ((3aR,5S,6aR)-2,2-dimethyl-6-methylenetetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate 
• 108-24-7 acetic anhydride 
• 1028262-50-1 Benzoic acid (2S,4R)-4,5-dihydroxy-3-methylene-tetrahydro-furan-2-ylmethyl ester 
• 6698-46-0 5-O-benzoyl-1,2-O-isopropylidene-α-D-ribofuranos-3-ulose 

Downstream Products

• 1026980-17-5 benzoic acid 4-acetoxy-5-(4-amino-5-oxo-5H-pyrido[2,3-d]pyrimidin-8-yl)-3-methylene-tetrahydro-furan-2-ylmethyl ester 

Relevant academic research and scientific papers

Synthesis and cytotoxicity of 4-amino-5-oxopyrido[2,3-d]pyrimidine nucleosides

A number of nucleoside analogues have been either used clinically as anticancer drugs or evaluated in clinical studies, while new nucleoside analogues continue to show promise. In this article, we report synthesis and cytotoxicity of a series of new pyrid

Un nouvel exemple de nucleoside a sucre ramifie insature: la desoxy-3'-methylidene-3'-adenosine

Starting from 5-O-benzoyl-3-C-methylidene-3-deoxy-1,2-O-isopropylidene-α-D-erythro-pentofuranose (11) the title compound 8 has been prepared.Its α-anomer (9) and the acyclic sugar nucleoside 10 have been obtained as by-products.Adenosine deaminase slowly deaminated 8, 9 being not affected.Compound 8 exhibited no antiviral activity, whereas one of its saturated analogues (13) inhibited the multiplication of the herpes-1 (HF) virus.