306961-33-1

Basic information

• Product Name: Benzeneacetaldehyde, a-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-
• CAS NO: 306961-33-1
• Molecular Formula: C24H26O2Si
• Molecular Weight: 374.555
• Mol File: 306961-33-1.mol

Chemical Properties

• CAS DataBase Reference: Benzeneacetaldehyde, a-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetaldehyde, a-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-(306961-33-1)
• EPA Substance Registry System: Benzeneacetaldehyde, a-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-(306961-33-1)

Safety Data

• Hazardous Substances Data: 306961-33-1(Hazardous Substances Data)

Upstream product

• 774-40-3 hydroxy-phenyl-acetic acid ethyl ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 404392-85-4 (tert-butyl-diphenyl-silanyloxy)-phenyl-acetic acid ethyl ester 

Downstream Products

• 681433-46-5 (1S,2R)-2-{[tert-butyl(diphenyl)silyl]oxy}-1-[(2R,6S)-6-ethoxy-5,6-dihydro-2H-pyran-2-yl]-2-phenylethanol 

Relevant articles and documents

Comparative Study of the Diastereoselective Addition of Allenyl Zinc Reagents to α-Alkoxy (or Silyloxy) Aldehydes and Imines. A Straightforward Synthesis of Amino Alcohols from Imines

The addition of allenylzinc bromides to α-chiral imines proceeds with very high diastereoselectivity. This result is in contrast with the addition to the corresponding aldehydes, leading to poor diastereoselectivity. The anti/anti adducts are explained by Felkin-Ahn and Gaudemar-Yamamoto models of the transition state.