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306966-56-3

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306966-56-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 306966-56-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,6,9,6 and 6 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 306966-56:
(8*3)+(7*0)+(6*6)+(5*9)+(4*6)+(3*6)+(2*5)+(1*6)=163
163 % 10 = 3
So 306966-56-3 is a valid CAS Registry Number.

306966-56-3Relevant articles and documents

Dual β2-adrenoceptor agonists-PDE4 inhibitors for the treatment of asthma and COPD

Shan, Wen-Jun,Huang, Ling,Zhou, Qi,Jiang, Huai-Lei,Luo, Zong-Hua,Lai, Ke-Fang,Li, Xing-Shu

, p. 1523 - 1526 (2012/04/04)

We designed and synthesized a novel class of dual pharmacology bronchodilators targeting both b2-adrenoceptor and PDE4 by applying a multivalent approach. The most potent dual pharmacology molecule, compound 29, possessed good inhibitory activity on PDE4B2 (IC50 = 0.278 μM, which was more potent than phthalazinone, IC50 = 0.520 lM) and possessed excellent relaxant effects on tracheal rings precontracted by histamine (pEC50 = 9.3).

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