306974-64-1

Basic information

• Product Name: ETHYL 4-(5-((2-ETHOXYPYRIMIDIN-5-YL)METHYL)-4-OXO-2-THIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)BENZOATE
• Synonyms: ETHYL 4-(5-((2-ETHOXYPYRIMIDIN-5-YL)METHYL)-4-OXO-2-THIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)BENZOATE
• CAS NO: 306974-64-1
• Molecular Formula: C₂₀H₂₀N₄O₄S
• Molecular Weight: 412.46
• Mol File: 306974-64-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ETHYL 4-(5-((2-ETHOXYPYRIMIDIN-5-YL)METHYL)-4-OXO-2-THIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)BENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-(5-((2-ETHOXYPYRIMIDIN-5-YL)METHYL)-4-OXO-2-THIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)BENZOATE(306974-64-1)
• EPA Substance Registry System: ETHYL 4-(5-((2-ETHOXYPYRIMIDIN-5-YL)METHYL)-4-OXO-2-THIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)BENZOATE(306974-64-1)

Safety Data

• Hazardous Substances Data: 306974-64-1(Hazardous Substances Data)

Upstream product

• 1314534-00-3 ethyl 3-(2-ethoxypyrimidin-5-yl)propionate 
• 1314533-99-7 ethyl 3-(2-ethoxypyrimidin-5-yl)acrylate 

Downstream Products

• 306974-70-9 GW1100 

Relevant articles and documents

Feasible synthesis of the GPR40 antagonist by contructing 2-thiouracil ring VIA acid mediated cyclization

GW1100 is an antagonist of GPR40 identified by high throughput screening recently. The feasible synthesis of GW1100 has been developed in mild conditions. The key step involves the cyclization of the 2-thiouracil heterocycle under acidic conditions at room temperature. The Japan Institute of Heterocyclic Chemistry.