307-22-2

Basic information

• Product Name: 1-CHLORO-6H-DODECAFLUOROHEXANE
• Synonyms: 1-CHLORO-6H-DODECAFLUOROHEXANE;1-CHLORO-6H-PERFLUOROHEXANE;6CHLORO-1H-PERFLUOROHEXANE;1-Chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluo;6Chloro-1H-perfluorohexane 97%;6Chloro-1H-perfluorohexane97%
• CAS NO: 307-22-2
• Molecular Formula: C₆HClF₁₂
• Molecular Weight: 336.51
• Mol File: 307-22-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 141-143°C
• Flash Point: 36.3°C
• Appearance: /
• Density: 1.641g/cm³
• Vapor Pressure: 29mmHg at 25°C
• Refractive Index: 1.284
• CAS DataBase Reference: 1-CHLORO-6H-DODECAFLUOROHEXANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLORO-6H-DODECAFLUOROHEXANE(307-22-2)
• EPA Substance Registry System: 1-CHLORO-6H-DODECAFLUOROHEXANE(307-22-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 307-22-2(Hazardous Substances Data)

Usage

General Description

1-Chloro-6H-dodecafluorohexane, also known as perfluorohexyl bromide, is a fluorinated organic compound with the molecular formula C6F12Cl. It is a colorless, odorless liquid that is used as a solvent and as a precursor for the synthesis of other fluorinated compounds. This chemical is commonly used in the production of pharmaceuticals, agrochemicals, and electronics. It is also used as a heat transfer fluid in cooling systems and as a propellant in aerosol products. Due to its high thermal stability and chemical inertness, 1-chloro-6H-dodecafluorohexane has a wide range of industrial and commercial applications. However, it is important to handle and use this chemical with caution, as it can be harmful if not properly controlled.

InChI:InChI=1/C6HClF12/c7-6(18,19)5(16,17)4(14,15)3(12,13)2(10,11)1(8)9/h1H

Upstream product

• 16486-97-8 1-Chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluoro-6-iodo-hexane 
• 91-66-7 N,N-diethylaniline 
• 100-61-8 N-methylaniline 
• 95-53-4 o-toluidine 
• 62-53-3 aniline 
• 106-47-8 4-chloro-aniline 
• 141-97-9 ethyl acetoacetate 
• 100-22-1 N,N,N',N'-tetramethyl-para-phenylenediamine 
• 95-68-1 2,4-Xylidine 
• 121-69-7 N,N-dimethyl-aniline 
• 149-30-4 2-Mercaptobenzothiazole 

Downstream Products

• 37881-62-2 perfluoroadipic acid difluoride 
• 355-66-8 octafluoro-adipic acid diamide 
• 336-07-2 1H,6H-perfluorohexane 

Relevant articles and documents

A FACILE METHOD FOR FLUOROALKYLATION OF ANILINE AND ITS DERIVATIVES

In the presence of tetrakis(triphenylphosphine)nickel, fluoroalkylation reactions of aniline and its derivatives occur under mild conditions, giving good yields of the corresponding o- and p-fluoroalkylaniline.The reaction shows regioselectivity.The hydrolytic behaviors of the products are also described.

Complexation and Photoinduced Electron-transfer Reaction between Perfluoroalkyl Iodides and N,N,N',N'-Tetramethylphenylene-1,4-diamine, Anilines and Piperazines

Treatment of tetrafluoro-1,2-diiodoethane 1a or dodecafluoro-1,6-diiodohexane 1b with N,N,N',N'-tetramethylphenylene-1,4-diamine 2 gave 1 + 1 solid complexes 3a or 3b in high yields.Complex 3a decomposed to give tetrafluoroethylene, iodine and 2 when irradiated with UV or heated.Complex 3b was converted into 6H-dodecafluorohexyl-N,N,N',N'-tetramethylphenylene-1,4-diamine 4 when irradiated with UV.On treatment of 1a and 1b with piperazine 6a and N,N'-dimethylpiperazine 6b, 1 + 1 solid complexes 7 were similarly obtained.However, heating or irradiating 7 gave no perfluoroalkylated products.Irradiating a mixture of 2 or anilines 13 and perfluoroalkyl iodides 10 in dimethylformamide also gave perfluoroalkylated products.The photoinduced electron transfer reaction involved radical cation 2*+ as a reactive intermediate which was detected by EPR techniques.