307-60-8

Basic information

• Product Name: Perfluorododecyl iodide
• Synonyms: Dodecane, 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12-pentacosafluoro-12-iodo-;dodecane,1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12-pentacosafluo;ro-12-iodo-;1-IODOPERFLUORODODECANE;PERFLUORODODECYL IODIDE;1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12-pentacosafluoro-12-iodododecane;pentacosafluoro-1-iodododecane;Perfluorododecyl iodide 97%
• CAS NO: 307-60-8
• Molecular Formula: C₁₂F₂₅I
• Molecular Weight: 745.99
• EINECS: 206-205-3
• Mol File: 307-60-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 95-98 °C(lit.)
• Boiling Point: 108-110 °C18 mm Hg(lit.)
• Flash Point: 110.8°C
• Appearance: /
• Density: 1.9588 (estimate)
• Vapor Pressure: 0.126mmHg at 25°C
• Refractive Index: 1.312
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• BRN: 1718343
• CAS DataBase Reference: Perfluorododecyl iodide(CAS DataBase Reference)
• NIST Chemistry Reference: Perfluorododecyl iodide(307-60-8)
• EPA Substance Registry System: Perfluorododecyl iodide(307-60-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 8
• TSCA: T
• HazardClass: IRRITANT
• Hazardous Substances Data: 307-60-8(Hazardous Substances Data)

Usage

Chemical Properties

yellow waxy chunks

Uses

Different sources of media describe the Uses of 307-60-8 differently. You can refer to the following data:
1. Perfluorododecyl Iodide self-assemble on a silicon nitride which are compatible with several applications such as biosensing.
2. Pentacosafluoro-1-iodododecane (1-Iodoperfluorododecane) has been used in E-screen assay to investigate the estrogenic activities of polyfluorinated iodine alkanes in MCF-7 cells.

InChI:InChI=1/C12F25I/c13-1(14,3(17,18)5(21,22)7(25,26)9(29,30)11(33,34)35)2(15,16)4(19,20)6(23,24)8(27,28)10(31,32)12(36,37)38

Upstream product

• 116-14-3 polytetrafluoroethylene 
• 423-39-2 1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane 
• 354-64-3 Pentafluoroethyl iodide 

Downstream Products

• 3042-22-6 2-phenyl-1H-pyrrole 
• 141246-55-1 2-perfluorododecanoylpyrrole 
• 305344-21-2 Dimethyl 5-(7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,17,17,18,18,18-pentacosafluoro-n-octadecyloxy)isophthalate 
• 1424373-37-4 pentacosafluorododecyldiphenylphosphine 
• 2043-57-4 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane 
• 2043-53-0 2-(n-perfluorooctyl)ethyl iodide 
• 2043-54-1 1-iodo-1H,1H,2H,2H-perfluorododecane 
• 30046-31-2 1-iodo-1H,1H,2H,2H-perfluorotetradecane 

Relevant articles and documents

PROCESS FOR PRODUCING FLUOROALKYL IODIDE TELOMER

A novel process for producing a fluoroalkyl iodide telomer is provided, which is able to obtain a fluoroalkyl iodide telomer having a desired chain length, efficiently. A fluoroalkyl iodide represented by the general formula RfI (wherein Rf is a C1-10 fluoroalkyl group) and tetrafluoroethylene are used as a telogen and a taxogen, respectively. These compounds are supplied to a distillation apparatus. In a reaction zone located in an intermediate part of the distillation apparatus, the compounds are subjected to a telomerization reaction in the presence of a metal catalyst with heating to generate a fluoroalkyl iodide telomer represented by the general formula Rf(CF2CF2)nI (wherein Rf is the same as defined above and n is an integer of 1-4). Thereafter, a fraction comprising the fluoroalkyl iodide telomer is separated by distillation.

METHOD FOR CONTINUOUS PRODUCTION OF A PERFLUOROALKYL IODIDE TELOMER

The present invention relates to a process for continuously producing a perfluoroalkyl iodide represented by the general formula Rf(CF2CF2)nI, wherein Rf is a C1-6 perfluoroalkyl and n is an integer from 1 to 4, the method comprising continuously supplying a perfluoroalkyl iodide as a telogen represented by the general formula RfI, wherein Rf is as defined above, and tetrafluoroethylene as a taxogen to a tubular reactor packed with a metal catalyst comprising a powdery spherical metal or a sintered metal; and conducting telomerization at a temperature of 60 to 160°C under a pressure of 0.1 to 5 MPa (gauge pressure). According to the present invention, medium-chain perfluoroalkyl iodides can be continuously and efficiently produced with little generation of impurities, such as hydrogen-containing organic compounds and the like.