30720-10-6 Usage
Chemical class
Pyrazolopyridine derivatives.
Potential use
Treatment of erectile dysfunction and other related conditions.
Mechanism of action
Inhibition of phosphodiesterase 5 (PDE5) enzyme.
Effect on cGMP levels
Blocking PDE5 action leads to increased levels of cyclic guanosine monophosphate (cGMP) in smooth muscle cells of the penis.
Physiological outcome
Relaxation of smooth muscle cells and increased blood flow in the penis.
Form
Ethyl ester, which is likely a prodrug intended to be converted into its active form within the body.
Further research
Needed to fully understand the potential therapeutic applications and mechanisms of action of 1-Benzyl-4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester.
Check Digit Verification of cas no
The CAS Registry Mumber 30720-10-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,7,2 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 30720-10:
(7*3)+(6*0)+(5*7)+(4*2)+(3*0)+(2*1)+(1*0)=66
66 % 10 = 6
So 30720-10-6 is a valid CAS Registry Number.
30720-10-6Relevant academic research and scientific papers
Unambiguous Synthesis of 4,7-Dihydro-4-oxo-1H-pyrazolopyridine - Further Comments on the "(N-C)-Rearrangement" of (2-Alkoxycarbonyl-vinylamino)pyrazols
Dorn, Helmut,Ozegowski, Ruediger
, p. 557 - 562 (2007/10/02)
4,7-Dihydro-4-oxo-1H-pyrazolopyridine 1a is synthesized by decarboxylation of 1-benzyl-5-carboxy-4-hydroxy-pyrazolopyridine 4b and debenzylation of 1-benzyl-4,7-dihydro-4-oxo-pyrazolopyridine 1b with sodium in liquid ammonia.The produ
