30720-65-1Relevant academic research and scientific papers
The 't-amino effect' of ortho-nitroso amines. Synthesis of 2,6-diaminoadenine derivatives from 6-(Dialkylamino)-5-nitrosopyrimidines
Del Carmen Ruiz, Maria,Vasella, Andrea
experimental part, p. 785 - 800 (2011/06/24)
The 't-amino effect' of amino-nitroso compounds was documented by preparing the (dialkylamino)-nitroso pyrimidines 4-18, and cyclising them under thermal conditions in high yields to the purine derivatives 19-32. The reactivity of the amino-nitroso-pyrimi
Tricyclic purine analogs derived from 2-amino-6-chloropurine and 2,6-diaminopurine and their methylated quaternary salts
Horejsi, Katerina,Pohl, Radek,Holy, Antonin
, p. 77 - 90 (2007/10/03)
A novel series of tricyclic, etheno-bridged purine analogs was sythesized from 2-amino-6-(substituted amino)-9-methylpurines by cyclization with chloroacetaldehyde, with particular focus on the regioselectivity of the cyclization reaction and fluorescence properties. The analogs as well as the starting purines were alkylated with iodomethane, affording a new class of quaternary salts with potential biological activity. Neither significant fluorescence nor cytostatic effect was found.
