30724-67-5

Upstream product

• 701-56-4 4-methoxy-N,N-dimethylanilne 
• 5961-59-1 N-methyl-N-(4-methoxyphenyl)amine 
• 108874-78-8 N-(4-methoxyphenyl)-N-methyl-S-phenylthiohydroxylamine 

Relevant academic research and scientific papers

LDA-promoted decomposition of benzenesulfenamides. A route to aminyl radicals by dioxygen oxidation of lithium amides

The LDA-promoted decomposition of N-monosubstituted sulfenamides 1a-d occurs through the formation of thioaminyl anions, which undergo oxidation either at sulfur, with formation of sulfonamides, or at nitrogen, with formation of thioaminyl radicals, depending on the nature of the 4'-substituent. The reaction of N,N-disubstituted sulfenamides 1e-h proceeds through the intermediacy of a lithium complex capable of generating aminyl radicals via sulfenyl group transfer to the di-iso-propylamido anion and subsequent aerial oxidation of the resulting lithium amides 3e-h.

PALLADIUM ASSISTED N-METHYL ACTIVATION OF p-SUBSTITUTED N,N-DIMETHYLANILINES

Intermediates in reaction of N,N-dimethylanilines with palladium(II) acetate were trapped by acetate ion or oxygen to give N-methyloxygenated and demethylated products, while the trapping by other anilines gave homo- and cross-coupling cyclodimers.The reactions proceed via radical cation formation induced by the palladium salt.