30739-27-6

Usage

Alias

3-Hydroxypropyl anthranilamide

Chemical Class

Benzamides

Structure

Contains a benzene ring with an attached amide group and an amino group

Molecular Weight

191.22 g/mol

Applications

Commonly used in the pharmaceutical industry

Utility

Acts as a building block for synthesizing various bioactive compounds and pharmaceutical drugs

Biological Activities

Exhibits potential biological activities

Therapeutic Effects

Studied for therapeutic effects in various diseases and disorders

Upstream product

• 118-48-9 isatoic anhydride 
• 156-87-6 propan-1-ol-3-amine 

Downstream Products

• 139193-06-9 3-(3-chloropropyl)quinazolin-4(3H)-one 
• 113642-38-9 <(benzenesulfonyloxy)-3 propyl>-3-3H-benzotriazine-1,2,3 one-4 
• 91532-05-7 <(p-toluenesulfonyloxy)-3 propyl>-3-3H-benzotriazine-1,2,3 one-4 
• 113675-68-6 3-[3-(4-Phenyl-cyclohexylamino)-propyl]-3H-benzo[d][1,2,3]triazin-4-one 
• 91532-01-3 3-<3-<4-(3-chlorophenyl)piperazin-1-yl>-propyl>-1,2,3-benzotriazin-4(3H)-one 
• 113642-41-4 3-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-3H-benzo[d][1,2,3]triazin-4-one 
• 113642-42-5 3-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-propyl}-3H-benzo[d][1,2,3]triazin-4-one 

Relevant academic research and scientific papers

Quinazolinone derivatives and production method and application thereof

The invention discloses quinazolinone derivatives and a production method and application thereof. The quinazolinone derivatives are synthesized by means of the simple and convenient method, the yields are high, the production cost is low, with a concentr

Nucleotides. Part LXXVIII: Double labeling of nucleosides and nucleotides

Several N(-hydroxyalkyl)-2,4-dinitroanilines were transformed into their phosphoramidites (see 5 and 6 in Scheme 1) in view of their use as fluorescence quenchers, and modified 2-aminobenzamides (see 9, 10, 18, and 19 in Scheme 1) were applied in model re

FIBRATE COMPOUNDS HAVING PPAR AGONIST ACTIVITY

There are provided derivatives having PPAR agonist activity. The derivatives include compounds and/or their pharmaceutically acceptable salts; the compounds having the formula (I) wherein A has the structure (II) or (III); X is chosen from -CH2-, -O-, -NH-, and -S-; Y is chosen from -O-, -NH-, and -S-; Z, which may be located in any position of substitution, is hydrogen or halogen; R1 and R2, which may be the same or different, are independently chosen from hydrogen and C1-C8 alkyl, or R1 and R2 together form a carbocyclic ring having from 4 to 6 carbon atoms; R3 is chosen from hydrogen and C1-C8 alkyl; R4, R5, and R6, which may be the same or different, are independently chosen from hydrogen and C1-C8 alkyl; and n is 1 to 6. Various embodiments and variants are provided. In accordance with other aspects, the invention also provides methods of producing a PPARα agonist activity in a mammal, the methods including administering to the mammal an effective amount of certain derivative(s) of the first aspect of the invention, a method of producing a PPARα agonist activity and a PPARα agonist activity in a mammal, the method including administering to the mammal an effective amount of certain derivative(s); and a pharmaceutical composition that includes the derivative(s) of the first aspect of the invention and one or more pharmaceutically-acceptable excipients. Various embodiments and variants are provided.

Triazolo and derivatives as chemokine inhibitors

Novel triazolo derivatives represented by the following formula and pharmaceutically acceptable salts thereof, as well as chemokine inhibitors containing the same as an effective component. These are useful as therapeutic agents for allergic diseases such

SYNTHESE ET ACTIVITE ANTI-DEPRESSIVE POTENTIELLE DE NOUVELLES TRIAZINE-1,2,3-ONES-4

Synthesis of new 1,2,3-triazin-4-ones as potential anti-depressants.A series of 1,2,3-triazin-4-ones was prepared and examined for potential anti-depressive activity by comparison with trazodone 2.Several of them show a potentiation of the central effects