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1H-Indole-5-sulfonamide(9CI) is a chemical compound characterized by the molecular formula C8H8N2O2S. It is a sulfonamide derivative of the heterocyclic aromatic organic compound indole. This versatile chemical is recognized for its potential as a building block in the pharmaceutical industry, particularly for the synthesis of a variety of drugs and compounds. Its unique properties position it as a precursor for the preparation of bioactive molecules and pharmaceutical ingredients, with applications spanning across anti-cancer, anti-inflammatory, and anti-microbial treatments. The presence of sulfur atoms in the compound further enhances its utility in synthetic transformations and chemical reactions within organic synthesis.

3074-27-9

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3074-27-9 Usage

Uses

Used in Pharmaceutical Industry:
1H-Indole-5-sulfonamide(9CI) is used as a building block for the synthesis of various drugs and compounds, leveraging its structural and chemical properties to contribute to the development of new pharmaceuticals.
1. As a Precursor for Bioactive Molecules:
1H-Indole-5-sulfonamide(9CI) is utilized as a precursor in the preparation of bioactive molecules, which are essential for the creation of pharmaceutical ingredients with specific therapeutic effects.
2. For the Development of Anti-Cancer Treatments:
In the realm of oncology, 1H-Indole-5-sulfonamide(9CI) is employed as a component in the development of new anti-cancer drugs, potentially contributing to treatments for a range of cancers.
3. For Anti-Inflammatory Drug Development:
1H-Indole-5-sulfonamide(9CI) is also used in the formulation of anti-inflammatory drugs, where its properties can help in managing inflammation and related conditions.
4. In Anti-Microbial Drug Synthesis:
1H-Indole-5-sulfonamide(9CI) plays a role in the synthesis of anti-microbial agents, which are crucial for combating various microbial infections.
5. For Organic Synthesis and Chemical Reactions:
Due to the presence of sulfur atoms, 1H-Indole-5-sulfonamide(9CI) is used in organic synthesis for carrying out synthetic transformations and facilitating chemical reactions, broadening its applications beyond direct pharmaceutical uses.

Check Digit Verification of cas no

The CAS Registry Mumber 3074-27-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,0,7 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3074-27:
(6*3)+(5*0)+(4*7)+(3*4)+(2*2)+(1*7)=69
69 % 10 = 9
So 3074-27-9 is a valid CAS Registry Number.

3074-27-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1H-indole-5-sulfonamide

1.2 Other means of identification

Product number -
Other names 5-Sulfamoyl-indol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3074-27-9 SDS

3074-27-9Relevant academic research and scientific papers

SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS

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Page/Page column 144, (2012/12/13)

Disclosed are compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein: W and Q and G are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bcl-2 family antiapoptotic proteins for the treatment of cancer; and pharmaceutical compositions comprising such compounds.

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