307492-67-7

Upstream product

• 182193-69-7 (S)-1-(p-methoxybenzyloxy)-2-methylpentan-3-one 
• 307492-63-3 (E)-(3S,4R,5S,6S)-7-(4-Methoxy-benzyloxy)-4,6-dimethyl-1-phenyl-hept-1-ene-3,5-diol 
• 307492-62-2 (E)-(2S,4R,5S)-5-Hydroxy-1-(4-methoxy-benzyloxy)-2,4-dimethyl-7-phenyl-hept-6-en-3-one 
• 14371-10-9 (E)-3-phenylpropenal 
• 307492-66-6 Acetic acid (E)-(1S,2R,3S)-3-acetoxy-1-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-5-phenyl-pent-4-enyl ester 

Downstream Products

• 307492-68-8 (1R,4R,5R,6S,E)-7-(tert-butyldiphenylsilyloxy)-4,6-dimethyl-1-phenylhept-1-ene-3,5-diyl diacetate 
• 307492-69-9 (3S,4R,5S,6S,E)-7-(tert-butyldiphenylsilyloxy)-4,6-dimethyl-1-phenylhept-1-ene-3,5-diol 

Relevant academic research and scientific papers

Asymmetric total synthesis of the myxobacteria metabolites crocacins A-D

The total syntheses of crocacins A-D are described. The key steps were a syn-aldol reaction followed by anti-reduction to secure the stereotetrad and acylation of an ene- or dienecarbamate to form the enamide. Crown Copyright

Total synthesis of (+)-crocacin C.

The first asymmetric synthesis of (+)-crocacin C (3) is described which served to confirm the absolute configuration of this compound. The key step in the sequence was the stereoselective assembly of the (E,E)-diene amide side chain by a Stille cross-coup