307534-84-5

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 3-(3,4-dimethoxyphenyl)-7-hydroxy-2-(trifluoromethyl)-
• CAS NO: 307534-84-5
• Molecular Formula: C18H13F3O5
• Molecular Weight: 366.293
• Mol File: 307534-84-5.mol

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 3-(3,4-dimethoxyphenyl)-7-hydroxy-2-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 3-(3,4-dimethoxyphenyl)-7-hydroxy-2-(trifluoromethyl)-(307534-84-5)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 3-(3,4-dimethoxyphenyl)-7-hydroxy-2-(trifluoromethyl)-(307534-84-5)

Safety Data

• Hazardous Substances Data: 307534-84-5(Hazardous Substances Data)

Upstream product

• 24126-98-5 1-(2,4-dihydroxyphenyl)-2-(3,4-dimethoxyphenyl)ethan-1-one 
• 407-25-0 trifluoroacetic anhydride 

Relevant articles and documents

Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals

The aminomethylation of hydroxylated isoflavones with 2-aminoethanol, 3-amino-1-propanol, 4-amino-1-butanol, and 5-amino-1-pentanol in the presence of excess formaldehyde led principally to 9-(2-hydroalkyl)-9,10-dihydro-4H,8H-chromeno[8,7-e][1,3]-oxazin-4-ones 4 and/or the tautomeric 7-hydroxy-8-(1,3-oxazepan-3-ylmethyl)-4H-chromen-4-ones 5. The ratio of these tautomers was dependent on solvent polarity, electronic effects of aryl substituents in the isoflavone and the structure of the amino alcohol. NMR studies confirmed the interconversion of tautomeric forms.

Synthesis of 3,4-dimethoxyisoflavone derivatives

2-(Un)substituted-3,4 -dimethoxy-7-hydroxyisoflavones were synthesized. Their derivatives substituted at the phenolic hydroxyl were prepared by alkylation and acylation. Aminomethyl derivatives were also prepared.