3077-30-3

Basic information

• Product Name: N,N-bis(2-hydroxyethyl)octanamide
• Synonyms: N,N-bis(2-hydroxyethyl)octanamide;N,N-Bis(2-hydroxyethyl)caprylamide;N,N-Bis(2-hydroxyethyl)caprylic amide
• CAS NO: 3077-30-3
• Molecular Formula: C₁₂H₂₅NO₃
• Molecular Weight: 231.3318
• EINECS: 221-362-8
• Mol File: 3077-30-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 392.2°C at 760 mmHg
• Flash Point: 191°C
• Appearance: /
• Density: 1.023g/cm³
• Vapor Pressure: 8.91E-08mmHg at 25°C
• Refractive Index: 1.482
• PKA: 14.13±0.10(Predicted)
• CAS DataBase Reference: N,N-bis(2-hydroxyethyl)octanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-bis(2-hydroxyethyl)octanamide(3077-30-3)
• EPA Substance Registry System: N,N-bis(2-hydroxyethyl)octanamide(3077-30-3)

Safety Data

• Hazardous Substances Data: 3077-30-3(Hazardous Substances Data)

Usage

General Description

"N,N-bis(2-hydroxyethyl)octanamide" is a chemical compound that belongs to the class of amides. It is a viscous liquid at room temperature and is commonly used as a surfactant and emulsifier in various industrial and personal care products. It is also employed as a thickening agent in cosmetic formulations and as a lubricant in metalworking fluids. The compound is synthesized by reacting octanoyl chloride with diethanolamine, resulting in the formation of N,N-bis(2-hydroxyethyl)octanamide. It is known for its ability to improve the stability and solubility of formulations, as well as its emollient and conditioning properties on the skin and hair.

InChI:InChI=1/C12H25NO3/c1-2-3-4-5-6-7-12(16)13(8-10-14)9-11-15/h14-15H,2-11H2,1H3

Upstream product

• 124-07-2 Octanoic acid 
• 111-42-2 2,2'-iminobis[ethanol] 

Relevant articles and documents

Low molecular weight PEI-based biodegradable lipopolymers as gene delivery vectors

Non-viral gene vectors play an important role in the development of gene therapy. In this report, different hydrophobic chains were introduced into low molecular weight (LMW) PEI-based biodegradable oligomers to form a series of lipopolymers (LPs), and their structure-activity relationships were studied. Results revealed that the nine polymers can condense plasmid DNA well to form nanoparticles with appropriate sizes (120-250 nm) and positive zeta-potentials (+25-40 V). In vitro experiments were carried out and it was found that LP2 showed much higher transfection efficiency both in the presence and in the absence of serum under the polymer/DNA weight ratio of 0.8 in A549 cells.